University of Vermont

The University of Vermont Cancer Center

trials_pedssarc

Pediatric Sarcomas Clinical Trials

The University of Vermont Cancer Center has many trials specifically focused on pediatric sarcomas cancer research.

Status: Active - Recruiting
Study Title: A Children's Oncology Group Protocol for Collecting and Banking Ewing Sarcoma Specimens
Purpose: This research study is collecting and storing samples of tumor tissue, bone marrow, and blood from patients with Ewing sarcoma.
ClinicalTrials.gov Identifier: NCT00899990
Primary/Site/Co Investigator: Alan C Homans
Contact: Alan Homans (802) 847-2850
Information: http://clinicaltrials.gov/ct2/show/NCT00899990?term=COG+AEWS07B1&rank=1
Institution Number: 00-327 COG AEWS07B1
Protocol Research Type: Cooperative Group
Status: Active - Recruiting
Study Title: A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens
Purpose: The purpose of this study is to collect and store samples of blood and tumor tissue from patients with osteosarcoma.
ClinicalTrials.gov Identifier: NCT00899275
Primary/Site/Co Investigator: Alan C Homans
Contact: Alan Homans (802) 847-2850
Information: http://www.clinicaltrials.gov/ct2/show/NCT00899275?term=COG+AOST06B1&rank=1
Institution Number: 00-327 COG AOST06B1
Protocol Research Type: Cooperative Group
Status: Active - Recruiting
Study Title: A Group Wide Protocol for Collecting and Banking Soft Tissue Sarcoma Specimens
Purpose: The purpose of this study is to collect and store tumor tissue, blood, and bone marrow samples from patients with soft tissue sarcoma that will be tested in the laboratory.
ClinicalTrials.gov Identifier: NCT00919269
Primary/Site/Co Investigator: Alan C Homans
Contact: Alan Homans (802) 847-2850
Information: http://www.clinicaltrials.gov/ct2/show/NCT00919269?term=POG+D9902&rank=1
Institution Number: 80-1 POG D9902
Protocol Research Type: Cooperative Group
Status: Active - Recruiting
Study Title: COG AEWS1031 - A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma
Purpose: This randomized phase III trial is studying combination chemotherapy in treating patients with non-metastatic extracranial Ewing sarcoma.
ClinicalTrials.gov Identifier: NCT01231906
Primary/Site/Co Investigator: Alan C. Homans
Contact: Alan Homans (802) 847-2850
Information: http://www.clinicaltrials.gov/ct2/show/NCT01231906?term=COG+AEWS1031&rank=1
Institution Number: M11-146
Protocol Research Type: Cooperative Group
Status: Active - Recruiting
Study Title: COG ARST08P1 - A Pilot Study to Evaluate Novel Agents (Temozolomide and Cixutumumab IMC-A12, Anti-IGF-IR Monoclonal Antibody, IND #100947, NSC #742460) in Combination with Intensive Multi-Agent Interval Compressed Therapy for Patients with High-Risk Rhabdomyosarcoma
Purpose: This clinical trial is studying the side effects and how well giving temozolomide and cixutumumab together with combination chemotherapy works in treating patients with metastatic rhabdomyosarcoma. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as cixutumumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Giving temozolomide and cixutumumab together with combination chemotherapy may kill more tumor cells.
ClinicalTrials.gov Identifier: NCT01055314
Primary/Site/Co Investigator: Alan C. Homans
Contact: Alan Homans (802) 847-2850
Information: http://www.clinicaltrials.gov/ct2/show/NCT01055314?term=COG+ARST08P1&rank=1
Institution Number: M11-167
Protocol Research Type: Cooperative Group
Status: Active - Recruiting
Study Title: COG ARST0921 - Recurrent/Refractory Rhabdomyosarcoma
Purpose: This clinical trial is studying the side effects and how well giving temozolomide and cixutumumab together with combination chemotherapy works in treating patients with metastatic rhabdomyosarcoma. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as cixutumumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Giving temozolomide and cixutumumab together with combination chemotherapy may kill more tumor ce
ClinicalTrials.gov Identifier: NCT01222715
Primary/Site/Co Investigator: Alan C. Homans
Contact: Alan Homans (802) 847-2850
Information: http://www.clinicaltrials.gov/ct2/show/NCT01055314?term=COG+ARST08P1&rank=1
Institution Number: M11-167
Protocol Research Type: Cooperative Group

Last modified December 05 2014 11:50 AM