University of Vermont

The University of Vermont Cancer Center


Head and Neck Cancer Clinical Trials

The University of Vermont Cancer Center has trials specifically focused on head and neck cancer research.

Status: Active - Recruiting
Study Title:
VCC 0905 – A Pilot Study of Evaluate Response to Neoadjuvant Chemotherapy with Cisplatin and Docetaxel Followed by Chemoradiation Therapy with Carboplatin in Stage IV Non-Metastatic Head and Neck Cancer
Purpose: The purpose of this study is to evaluate the effectiveness of neoadjuvant chemotherapy (chemotherapy given before radiotherapy) using cisplatin and docetaxel followed by carboplatin chemotherapy  given at the same time as radiotherapy in the treatment of head and neck cancer.  Some studies have used neoadjuvant chemotherapy with 3 drugs (cisplatin, docetaxel and 5-fluorouracil) to try to shrink the tumor before  radiation therapy. However such intense chemotherapy may be associated with significant toxicity. We will be testing neoadjuvant chemotherapy with only two drugs (cisplatin and docetaxel) followed by chemoradiation therapy with only carboplatin to evaluate if tumor response can be achieved with less toxicity. Identifier: NCT00982436
Primary/Site/Co Investigator: Julie Olin, MD
Contact: Karen Wilson (802) 656-4101
Institution Number: CHRMS M09-269, VCC 0905
Protocol Research Type: Investigator Initiated

Last modified February 18 2016 02:03 PM