Undergraduate, PhD and MD/PhD students, Post-doctoral fellows, MD fellows:
Historically, researchers have employed a reductionist approach to scientific questions, in which tissues/systems/organs are dissected to their most basic components in order to define the mechanims underying biological function. This approach has yielded volumes of important information about the basic biology of human health and disease. Over the last several decades, however, there has been a strong push to "translate" our basic knowledge into treatments for clinical problems.
Our laboratory strives toward this objective by evaluating human skeletal muscle physiology from the whole body to the molecular level. Our work seeks to identify the fundamental defects that underlie muscle atrophy and dysfunction in chronic disease, disuse and aging, with the long-term goal of better defining cellular and molecular targets for therapeutic interventions designed to delay or correct physical disability. We also investigate the utility of various therapeutic approaches to define their effects on muscle structure, function and metabolism in patients from the whole body to the molecular level. Because of this translational approach, our lab provides an array of research training experiences that can span the range from the bench to the bedside.
We are always looking for enthusiastic young scientists/clinicians to join our team. Opportunities exist for federally funded postdoctoral and graduate studies. If interested, please contact Dr. Toth to discuss the possibility of becoming a member of our research group.
Last modified December 21 2010 12:44 PM