Translational Studies of Human Skeletal Muscle
Our studies evaluate skeletal muscle structure, function and metabolism at the whole body, tissue, single cell and molecular level in humans using a variety of research techniques. The focus of these studies is to understand the effects of:
- chronic disease,
- muscle disuse and
Our long-range goal is to understand the cellular and molecular mechanisms whereby these conditions regulate skeletal muscle size, metabolism and function and the potential utility of therapeutic interventions to counter physical disability.
On-going projects strive to understand how chronic disease in the elderly impairs muscle function and the utility of resistance exercise to correct these defects.
On-going projects seek to determine in elderly volunteers how skeletal muscle adapts to chronic muscle disuse and the remedial effects of resistance exercise training.
On-going projects with our collaborators focus on defining how aging affects skeletal muscle functionality at the whole muscle, single fiber and molecular levels.
Last modified August 16 2012 04:08 PM