University of Vermont

College of Medicine

Department of Pharmacology

Bio for Jonathan Ledoux
Jonathan Ledoux

Jonathan Ledoux


Contact Information

Education

Ph. D. in Physiology 1999-2004  Regulatory mechanisms of calcium-activated chloride channels in vascular smooth muscle cells. Supervisor: Dr Normand Leblanc Co-Supervisor: Dr Rémy Sauvé Montreal Heart Institute University of Montreal, Montreal
M. Sc. in Physiology Direct-Through to Ph. D. 1998-1999 Regulatory mechanisms of calcium-activated chloride channels in vascular smooth muscle cells. Supervisor: Dr Normand Leblanc Montreal Heart Institute University of Montreal, Montreal
B. Sc. in Biological Sciences 1995-1998 University of Montreal, Montreal

Awards and Honors

Fellowships

Canadian Institutes of Health Research (IRCS). 2005-2008
Fonds de recherche en Santé du Québec (FRSQ). 2004-2005
Heart and Stroke Foundation of Canada. 2005
- Declined
Montreal Heart Institute. 2003
- Declined
Scholarships

Canadian Institutes of Health Research (IRCS). 2000-2003
Heart and Stroke Foundation of Canada. 2000
- Declined
Excellence Awards

J.A. DeSève Foundation 2003
Faculty of Graduate Studies, 2000, 2001,
University of Monrtéal. 2002

Publications

Ledoux J, Greenwood I A and Leblanc N. Dynamics of Ca2+-dependent chloride channel modulation by niflumic acid in rabbit coronary arterial myocytes. Mol. Pharmacol. 67(1):163-73, 2005.
Greenwood I A, Ledoux J, Sanguinetti A, Perrino B A, Leblanc N. Calcineurin Aa but not Aß augments ICl(Ca) in rabbit pulmonary artery smooth muscle cells. J. Biol. Chem. 279(37):38830-7, 2004.
Ledoux J, Greenwood I A and Leblanc N. Modulation of Ca2+-activated chloride channels by Calcineurin in coronary arterial myocytes. J. Physiol. 552(Pt 3):701-14, 2003.
Ledoux J, Gee D M and Leblanc N. Increased peripheral resistance in heart failure: New evidence suggests an alteration in vascular smooth muscle function. B. J. Pharm, 139: 1245-1248, 2003.
Greenwood I A, Ledoux J and Leblanc N. Differential regulation of Ca2+-activated Cl- currents in rabbit arterial and portal vein smooth muscle cells by Ca2+/Calmodulin-dependent kinase. J. Physiol, 534(Pt 2): 395-408, 2001.
Ledoux J, Chartier D and Leblanc N. Inhibitors of Calmodulin-dependent protein kinase are non-specific blockers of voltage-dependent K+ channels in vascular myocytes. JPET 290:1165-1174, 1999.