University of Vermont

College of Medicine

Department of Pharmacology

Bio for Alan K. Howe, Ph.D.
Alan K. Howe, Ph.D.

Alan K. Howe, Ph.D.

Associate Professor
Department of Pharmacology

Contact Information
Office Location:
Health Sci Rsrch Facility, Rm 322




1996 Ph.D. Northwestern University, Evanston IL, Tumor Cell Biology

1990 B.S. University of New Hampshire, Durham NH, Biochemistry

Awards and Honors

2010-2011 Nominee, Silver Stethoscope Award for Teaching Excellence, UVM College of Medicine

2010 Invited Speaker, Gordon Research Conference on Signaling by Adhesion Receptors

2010 Distinguished Alumnus Speaker, Lineberger Comprehensive Cancer Center Postdoctoral Fellow  
          Training Grant, University of North Carolina at Chapel Hill

2001 Recipient, Howard Temin Career Award (NCI)

1999-2001 Postdoctoral fellow, American Cancer Society

1999 UNC-CH Nominee, Burroughs Wellcome Fund Career Award in the Biomedical Sciences

1996 Fellow, Lineberger Comprehensive Cancer Center Postdoctoral Training Award

1994-1995 Graduate fellow, Ingberman Charitable Trust

1991-1992 Graduate Fellow, Chicago Baseball Cancer Charities, Northwestern University

1990 Graduate Fellow, Carcinogenesis Training Grant, Northwestern University

1990 Graduated cum laude, University of New Hampshire


Phosphoprotein detection reagent and methods of making and using the same; U.S. Patent No. 7,799,526 (Licensed by InvitrogenTM)


2012 Caldwell, G., Howe, A.K., Nickl, C., Dostmann, W., Ballif, B., and Deming, P.. Direct modulation of the Protein Kinase A catalytic subunit by receptor tyrosine kinases. J. Biochem., 113(1):39-48.  doi: 10.102/jcb.23325, Jan. 2012.

2011 McKenzie, A.J., Campbell, S.L., Howe, A.K..  Protein Kinase A activity and anchoring are required for ovarian cancer cell migration and invasion.  PLoS One, 6(10):e26552.  Epublished Oct. 19, 2011.

2011 Langevin H.M., Bouffard N.A., Fox J.R., Palmer B.M., Wu J., Iatridis J.C., Barnes W.D., Badger, G.J., and Howe, A.K.. Fibroblast cytoskeletal remodeling contributes to connective tissue tension. J. Cell. Physiol., 226(5):1166-1175.  doi:  10.1002/jcp.22442, May 2011.

2011 Howe, A.K.  Cross-talk between calcium and protein kinase A in the regulation of cell migration.  Curr Opin Cell Biol. 2011 Oct; 23(5):554-561.  Epubl 2011 June 12.

2010 Langevin, H.M., Storch, K.N., Snapp, R.R., Boffard, N.A., Badger, G.J., Howe, A.K., Taatjes, D.J..  Tissue stretch induces nuclear remodeling in connective tissue fibroblasts.  Histochem Cell Biol. 113(4):405-415. April 2010.

2009 Rivard, R.L., Birger, M., Gaston, K.J., and Howe A.K.. AKAP-independent localization of type-II protein kinase A to dynamic actin microspikes. Cell Motil Cytoskel. 66:693-709, 2009.

For a complete list of Alan K. Howe's publications, please visit PubMed.