University of Vermont

College of Medicine

Department of Pharmacology

Bio for David Hill-Eubanks, Ph.D.
David Hill-Eubanks, Ph.D.

David Hill-Eubanks, Ph.D.

Research Assistant Professor
Department of Pharmacology

Contact Information
Office Location:
Given B-303

Awards and Honors

1979 Cum Laude graduate, Rice University

1997 SmithKline Beecham Student Pharmacology Award Recipient


For a complete list of David Hill-Eubanks's publications, please visit PubMed.

2015  Collier DM, Hill-Eubanks DC, Nelson MT.  Orchestrating Ca2+ influx through CaV1.2 and CaV3.x channels in human cerebral arteries.  J Gen Physiol.  doi:  10.1085/jgp.201511411.  PMID:  26009543, PMCID:  PMC4442783

2015  Dabertrand F, Kroigaard C, Bonev AD, Cognat E, Dalsgaard T, Domenga-Denier V, Hill-Eubanks DC, Brayden JE, Joutel A, Nelson MT.  Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.  Proc Natl Acad Sci USA.  doi:  10.1073/pnas.1420765112.  PMID:  25646445, PMCID:  PMC4343103

2014  Hill-Eubanks DC, Gonzales AL, Sonkusare SK, Nelson MT.  Vascular TRP channels:  performing under pressure and going with the flow.  Physiology (Bethesda).  doi:  10.1152/physiol.00009.2014.  PMID:  25180264, PMCID:  PMC4214829

2014  Sonkusare SK, Dalsgaard T, Bonev AD, Hill-Eubanks DC, Kotlikoff MI, Scott JD, Santana LF, Nelson MT.  AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.  Sci Signal.  doi:  10.1126/scisignal.2005052.  PMID:  25005230, PMCID:  PMC4403000

2014  Gonzales AL, Yang Y, Sullivan MN, Sanders L, Dabertrand F, Hill-Eubanks DC, Nelson MT, Earley S.  A PLCy1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries. Sci Signal.  doi:  10.1126/scisignal.2004732.  PMID:  24866019, PMCID:  PMC3170587

2014  Longden TA, Dabertrand F, Hill-Eubanks DC, Hammack SE, Nelson MT.  Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function.  Proc Natl Acad Sci USA.   doi:  10.1073/pnas.1401811111.  PMID:  24808139, PMCID:  PMC4034203

2013  Dunn KM, Hill-Eubanks DC, Liedtke WB, Nelson MT.  TRPV4 channels stimulate Ca2+ induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses.  Proc Natl Acad Sci USA.  doi:  10.1073/pnas.1216514110.  PMID:  23530219, PMCID:  PMC3625327

2013  Dabertrand F, Hannah RM, Pearson JM, Hill-Eubanks DC, Brayden JE, Nelson MT.  Prostaglandin E2, a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles.  J Cereb Blood Flow Metab.  doi:  10.1038/jcbfm.2013.9.  PMID:  23385200, PMCID:  PMC3618402

2012  Sonkusare SK, Bonev AD, Ledoux J, Liedtke W, Kotlikoff MI, Heppner TJ, Hill-Eubanks DC, Nelson MT.  Elementary Ca2+ sginals through endothelial TRPV4 channels regulate vascular function.  Science.  doi:  10.1126/science.1216283.  PMID:  22556255. PMCID:  PMC3715993.  Editor's Choice (L.B. Ray, Blood Pressure Gauge.  Sci. Signal.  5, 3c131), featured in a Perspective in the same issue and a Podcast:   

2011  Hill-Eubanks DC, Werner ME, Heppner TJ, Nelson MT. Calcium Signaling in Smooth Muscle. Cold Spring Harb Perspect Biol.  doi: 10.1101/cshperspect.a004549.   PMID:  21709182, PMCID:  PMC3181028

2010  Hill-Eubanks DC, Werner ME, Nelson MT. Local elementary purinergic-induced Ca2+ transients: from optical mapping of nerve activity to local Ca2+ signaling networks. J Gen Physiol.  doi:  10.1085/jgp.201010402.  PMID:  20660658, PMCID:  PMC2912073

2008  Layne JJ, Werner ME, Hill-Eubanks DC, Nelson MT. NFATc3 regulates BK channel function in murine urinary bladder smooth muscle. Am J Physiol Cell Physiol.  doi:  10.1152/ajpcell.00435.2007.  PMID:  18579799, PMCID:  PMC2544435

2005  Gonzalez Bosc LV, Layne JJ, Nelson MT, Hill-Eubanks DC.  Nuclear factor of activated T cells and serum response factor cooperatively regulate the activity of alpha-actin intronic enhancer. J Biol Chem.  doi:  10.1074/jbc.M411972200.  PMID:  15857835

2004  Gonzalez Bosc LV, Wilkerson MK, Bradley KN, Eckman DM, Hill-Eubanks DC, Nelson MT.  Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase. J Biol Chem.  doi:  10.1074/jbc.M312920200.  PMID:  14688253