Department of Pathology
Taatjes Lab Research
Microscopy Imaging Center: This is a College of Medicine, as well as Vermont Cancer Center Core Facility. The facility currently consists of a JEOL 1400 transmission electron microscope, a JEOL 6060 scanning electron microscope with an Oxford INCA energy dispersive spectroscopy system, a BioRad MRC 1024 confocal scanning laser microscope, a Zeiss LSM 510 META confocal scanning laser microscope, an Olympus BX50 wide-field fluorescence imaging system with QImaging Retiga 2000R digital camera, a Zeiss Axioscope wide-field fluorescence microscopy system, an Olympus inverted IX70 microscope with QImaging Retiga 2000R digital camera, an Applied Biophysics Electric Cell Substrate Impedance Sensing system, a CompuCyte laser scanning cytometer, an Arcturus laser capture microdissector, an Asylum Research MFP-3D-BIO atomic force microscope, and dedicated Dell workstations for image analysis and processing, with attached flat bed scanners, and the image analysis software packages MetaMorph from Universal Imaging (now Molecular Devices), Volocity from Improvision, Inc., and Stereo Investigator from MicroBrightfield, Inc.
I am also responsible for directing the clinical electron microscopy in the Department of Pathology, and assuring compliance of the laboratory with College of Academic Pathologists (CAP) guidelines. The Microscopy Imaging Center was recently awarded accreditation by the Commission on Laboratory Accreditation of CAP.
Research: I am currently involved in studies using multimodal imaging techniques in investigations of cardiovascular disease, environmental pathology, membrane fusion, fibroblast response to stretching, and platelet reactivity.
Teaching: I teach in Pathology and Anatomy & Neurobiology graduate level courses, as well as a week-long course at the Jackson Laboratory in Bar Harbor, Maine.
Last modified June 11 2012 12:18 PM