University of Vermont

College of Medicine

Department of Pathology and Laboratory Medicine

Bio for Neil A. Zakai, M.D., M.Sc.
Neil A. Zakai, M.D., M.Sc.

Neil A. Zakai, M.D., M.Sc.

Associate Professor of Medicine, Hematology/Oncology Division, Department of Medicine
Associate Professor of Pathology & Laboratory Medicine

Contact Information
(802) 656-3154
Office Location:
Colchester Research Facility, 360 South Park Drive, Colchester, VT 05446

Clinical Expertise

-  The care of patients with venous thrombosis and it’s complications
-  Evaluation of patients for inherited and acquired hyper-coagulable syndromes
-  Evaluation and management of patients with premature arterial vascular disease and the role of  novel risk factors
-  Evaluation and management of non-malignant disorders of red cells, white cells, and platelets


1992-1996    Johns Hopkins University, Baltimore, MD  -  BA in Biology and French 
1996-2000    University of Virginia School of Medicine, Charlottesville, VA  -  MD 
2000-2003    University of Vermont / Fletcher Allen Health Care, Burlington, VT – Internal Medicine Residency
2003-2004    University of Vermont / Fletcher Allen Health Care, Burlington, VT – Chief Medical Resident
2004-2007    Brown University, Providence, RI – Fellowship in Hematology & Oncology
2007-2009    Harvard School of Public Health, Boston, MA  -  Masters in Epidemiology - MSc

Certification/Board Eligibility

2003  Board Certified in Internal Medicine (recertified in 2013)
2007  American Board of Internal Medicine Subspecialty in Medical Oncology
2007  American Board of Internal Medicine Subspecialty in Hematology

Research Interests

-  The epidemiology and risk factors for arterial and venous thrombosis with an emphasis on the roles of novel risk factors such as inflammation and coagulation biomarkers. 
-  Defining clinical risk factors for and impact of venous thrombosis in hospitalized patients with an emphasis on improved risk stratification tools and delivery of appropriate anticoagulation.
- The epidemiology of the causes and consequences of anemia especially in the elderly and diverse racial groups

Professional Societies

American Society of Hematology
American Society of Clinical Oncology
American Heart Association, Council on Epidemiology and Prevention
International Society of Thrombosis and Haemostasis


2016 Moore JX, Zakai NA, Mahalingam M, Griffin RL, Irvin MR, Safford MM, Baddley JW, Wang HE. Hemostasis biomarkers and risk of sepsis: the REGARDS cohort. J Thromb Haemost. 2016 Aug 11. PMID: 27512924
2016 Cushman M, O'Meara ES, Heckbert SR, Zakai NA, Rosamond W, Folsom AR. Body size measures, hemostatic and inflammatory markers and risk of venous thrombosis: The Longitudinal Investigation of Thromboembolism Etiology. Thromb Res. 2016 Aug;144:127-32. PMID: 27328432
2016 Kancherla V, Garn JV, Zakai NA, Williamson RS, Cashion WT, Odewole O, Judd SE, Oakley GP Jr. Multivitamin Use and Serum Vitamin B12 Concentrations in Older-Adult Metformin Users in REGARDS, 2003-2007. PLoS One. 2016 Aug 11;11(8):e0160802. PMID: 27513580
2015 Winters JP, Callas PW, Cushman M, Repp AB, Zakai NA.Central venous catheters and upper extremity deep vein thrombosis in medical inpatients: the Medical Inpatients and Thrombosis (MITH) Study. J Thromb Haemost. 2015 Dec;13(12):2155-60. PMID: 26340226
2015 Zakai NA. Superficial venous thrombosis: deeper than meets the eye? Blood. 2015 Jan 8;125(2):208-9. PMID: 25573964
2015 O'Neal WT, Soliman EZ, Howard G, Howard VJ, Safford MM, Cushman M, Zakai NA.Inflammation and hemostasis in atrial fibrillation and coronary heart disease: The REasons for Geographic And Racial Differences in Stroke study.Atherosclerosis. 2015 Nov;243(1):192-7.PMID: 26398291
2015 Bell EJ, Folsom AR, Lutsey PL, Selvin E, Zakai NA, Cushman M, Alonso A. Diabetes mellitus and venous thromboembolism: A systematic review and meta-analysis. Diabetes Res Clin Pract. 2015 Nov 10. pii: S0168-8227(15)00420-9.PMID: 26612139
2015 Zakai NA. Superficial venous thrombosis: deeper than meets the eye? Blood. 2015 Jan 8;125(2):208-9. doi: 10.1182/blood-2014-11-612549. PMID: 25573964

2015 Olson NC, Cushman M, Judd SE, McClure LA, Lakoski SG, Folsom AR, Safford MM, Zakai NA. American Heart Association's Life's Simple 7 and risk of venous thromboembolism: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study.J Am Heart Assoc. 2015 Feb 27;4(3):e001494. doi: 10.1161/JAHA.114.001494. PMID: 25725088

For a complete list of Neil Zakai's publications, please visit Google Scholar