University of Vermont

College of Medicine

Department of Pathology and Laboratory Medicine

Bio for Albert van der Vliet, Ph.D.
Albert van der Vliet, Ph.D.

Albert van der Vliet, Ph.D.

Professor
Department of Pathology


Contact Information
E-mail: Albert.van-der-Vliet@uvm.edu
Office Location:
Given Bldg D205

Website

van der Vliet Lab

Education

1987  B.S./M.S. Subfaculty of Chemistry, Faculty of Mathematics and Physical Sciences, Vrije Universiteit, Amsterdam, The Netherlands
1991 Ph.D. Department of Pharmacochemistry, Faculty of Chemistry, Vrije Universiteit, Amsterdam, The Netherlands

Expertise

The main goal of the van der Vliet laboratory is to unravel the molecular mechanisms by which biological and environmental oxidants contribute to lung cell injury, inflammation, and remodeling, as major features of chronic lung diseases such as asthma, COPD and lung cancer.

Research Interests

Nitric oxide synthases and NADPH oxidases in airway biology and pathology; Oxidant mechanisms in inflammation; Chemistry and biology of reactive oxygen and nitrogen species; Environmental oxidants and electrophiles; Lung epithelial cell biology and signaling; Chemical mechanisms of protein oxidation; Proteomic analysis of oxidation and alkylation targets; Antioxidant enzymes and micronutrients.

Academic Appointments

2008 - Present Professor, Department of Pathology, College of Medicine, University of Vermont, Burlington, VT
2002 -2008 Associate Professor, Department of Pathology, College of Medicine, University of Vermont, Burlington, VT
2001 - 2002 Associate Professor in Residence, Division of Pulmonary/Critical Care Medicine, Department of Internal Medicine, University of California, Davis
1999 - 2001 Assistant Professor in Residence, Division of Pulmonary/Critical Care Medicine, Department of Internal Medicine, University of California, Davis.
1997 - 1999 Assistant Research Biochemist, Division of Pulmonary/Critical Care Medicine, Department of Internal Medicine, University of California, Davis
1995 Visiting Scientist, Pharmacology Group, King's College, Chelsea Campus, University of London, U.K.
1993 - 1997 Postdoctoral Researcher, Division of Pulmonary/Critical Care Medicine, Department of Internal Medicine, University of California, Davis
1991 - 1993 Postdoctoral Researcher, Division of Molecular Pharmacology,Department of Pharmacochemistry, Vrije Universiteit, Amsterdam, The Netherlands

Awards and Honors

1994  Young Investigator Award, The Oxygen Society
1994-1996   Postdoctoral Fellowship, American Heart Association, California Affiliate
1996-1998  Parker B. Francis Fellowship Award in Pulmonary Research, Francis Family Foundation
1999  Joan Oettinger Memorial Award, UC Davis School of Medicine

Publications

2011 Hristova M, Spiess PC, Kasahara DI, Randall MJ, Deng B, van der Vliet A. The Tobacco Smoke Component Acrolein Suppresses Innate Macrophage Responses by Direct Alkylation of c-Jun-N-terminal Kinase. Am J Respir Cell Mol Biol. 2011 Jul 21.

2011 Aesif SW, Kuipers I, van der Velden J, Tully JE, Guala AS, Anathy V, Sheely JI, Reynaert NL, Wouters EF, van der Vliet A, Janssen-Heininger YM. Activation of the glutaredoxin-1 gene by nuclear factor ?B enhances signaling. Free Radic Biol Med. 2011 Jun 27

2011 Spiess PC, Deng B, Hondal RJ, Matthews DE, van der Vliet A. Proteomic profiling of acrolein adducts in human lung epithelial cells. J Proteomics. 2011 Jun 17

2011 Akaike T, Vliet A, Eaton P. Frontiers in nitric oxide and redox signaling. Nitric Oxide. 2011 Aug 1;25(2):57-8.

2011 van der Vliet A, Bove PF. Purinergic signaling in wound healing and airway remodeling. Subcell Biochem. 2011;55:139-57.
For a complete list of Albert van der Vliet's publications, please visit PubMed.