University of Vermont

College of Medicine

Department of Pathology and Laboratory Medicine


About Us

Message from the Chair

The Department of Pathology and Laboratory Medicine is responsible for all clinical testing at The University of Vermont Medical Center, our academic medical center and integrated delivery system. In the clinical pathology laboratory we do 2.8 million tests per year, 38,000 surgical pathology cases, 60,000 cytology cases and 120 autopsies. The laboratory facilities are part of a new outpatient building that is directly connected to our acute care facility. The laboratory offers state of the art diagnostics and consultation to our academic and community physician. Our pathology group includes sub-specialized clinician scientists in every discipline. We are also part of the North East Clinical Laboratory Alliance (NECLA) which is a network of all the hospital based clinical laboratories in Vermont as well as some in New York and New Hampshire. Our academic laboratory is the regional reference laboratory for the network in partnership with the Mayo Clinical Laboratories in Rochester Minnesota.

Our established research programs in Environmental, Cardiovascular and Experimental Pathology include 39 funded programs of which nine are new awards this past year. The Cardiovascular research group has one of the pre-eminent biomarker/biosensor laboratories in the country with a focus on molecular and genetic epidemiology. The research interests in Environmental Pathology can be grouped into three broad areas: 1) Environmental Lung Disease, 2) Cell Signaling in Proliferation, Injury, and 3) Apoptosis and DNA Damage/Genetic Toxicology. These programs are focused on delineating the specific molecular and pathological effects of physiologically relevant doses of environmental agents on specific target cells in the lung and other organs. Our Division of Experimental Pathology translational research focus often puts us in the top 10% for USCAP meeting invited presentations.

The National Institutes of Environmental Health Sciences (NIEHS) Environmental Pathology Training Grant (T32 award), funded since 1981, presently supports seven graduate students and two postdoctoral fellows in laboratories from several departments within the College.

We offer a Ph.D. through the Cell and Molecular Biology program. Our highly competitive clinical training programs include 16 residents and three fellowships: Cytopatholog, Dermatopathology and Surgical Pathology. The pathology faculty are routinely nominated for Vermont Integrated Curriculum (VIC) teaching awards. Most recently, the class of 2010 presented our team with the "outstanding department award." Our faculty also instruct and mentor students in the UVM College of Nursing and Health Sciences and The University of Vermont Medical Center AHC School of Cytotechnology, whose students score at the top on their national qualifying exams annually.

Debra G.B. Leonard, M.D., Ph.D.
Chairperson and Professor of Pathology



Our research and education facilities are located on or nearby the University of Vermont campus, which is adjacent to our teaching partner, The University of Vermont Medical Center. Our team is housed in the Given Medical Building, Health Science Research Facility, the Courtyard at Given, and the nearby Colchester Research Facility. Our Burlington home is nestled between the shores of Lake Champlain and the vistas of the Green Mountains. Learn more about living in Burlington.

We established and manage the following two state-of-the-art pathology research facilities, essential College of Medicine core facilities.
Laboratory for Clinical Biochemistry Research

The focus of the Laboratory for Clinical Biochemistry Research (LCBR) is on understanding risk factors for heart disease, stroke, venous thrombosis, obesity, diabetes, aging, and frailty using a wide variety of assays in population and family-based research settings, particularly in the areas of coagulation, fibrinolysis, thrombosis, inflammation, and immune system function. These results are linked to animal model studies, especially research in murine atherosclerosis. The LCBR is located near UVM's main medical campus in Colchester, Vermont.

Microscopy Imaging Center

The Microscopy Imaging Center (MIC) is a multi-user resource for the collection and analysis of biological images for clinical and research applications. At the light and electron microscopic levels, it provides state of the art, quality assured, morphologically oriented services.

Last modified November 12 2014 12:20 PM