Osteoporosis is defined as clinically relevant loss of bone mineral density or the presence of a fragility fracture and is a major health issue facing our aging population, particularly among postmenopausal women. Osteoporosis affects 10 million Americans and 18 million more are at risk; 80% of those at risk are women. It is a disease with roughly $6 billion in direct health care costs annually in the U.S. Current projects include studies to describe bone mineral density variations in a population of subjects with spinal stenosis, a specific degenerative disorder. Osteoporosis is a treatable condition in which intervention has been shown to decrease fracture risk. Identifying any subset of subjects with a high prevalence of the disorder can improve early detection, which is the most effective care available for this disorder.