University of Vermont

College of Medicine

Department of Obstetrics, Gynecology & Reproductive Sciences

Bio for Natalia Gokina, Ph.D.
Natalia Gokina, Ph.D.

Natalia Gokina, Ph.D.

Associate Professor
Department of Obstetrics, Gynecology and Reproductive Sciences


Contact Information
E-mail: Natalia.Gokina@uvm.edu
Phone:
802-656-1205
Office Location:
OB/GYN & Reproductive Sciences, Given Room C-209, 89 Beaumont Avenue, Burlington, VT 05405

Education

1985     Ph.D. - Ukranian Academy of Sciences, Kiev, Ukraine, Physiology
1974     M.S. - Physiology Kiev State University, Kiev, Ukraine
1974     B.S. - Kiev State University, Kiev, Ukraine, Physiology

Research Interests

Dr. Gokina’s primary research interest is in cardiovascular physiology, specifically, control of vascular smooth muscle and endothelial cell calcium and membrane potential during pregnancy, and in the signal transduction mechanisms underlying arterial reactivity.  Current research in Dr. Gokina’s lab is focused on understanding cellular and molecular mechanisms of uteroplacental vascular dysfunction in diabetic pregnancy.

Research Grants

NIH, National Heart, Blood, and Lung Institute 
Calcium Signaling in the Cerebrovascular Unit in Health and Disease (PI: Cipolla)
Collaborator: Natalia Gokina, Ph.D.     07/2010 - 06/2015

Publications

Gokina NI, Chan SL, Chapman AC, Oppenheimer K, Jetton TL, Cipolla MJ. Inhibition of PPAR? during rat pregnancy causes intrauterine growth restriction and attenuation of uterine vasodilation. Front Physiol. 2013 Jul 23;4:184. doi: 10.3389/fphys.2013.00184. eCollection 2013. PubMed PMID: 23888144; PubMed Central PMCID: PMC3719025.
Cipolla MJ, Sweet JG, Gokina NI, White SL, Nelson MT. Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation. J Cereb Blood Flow Metab. 2013 Oct;33(10):1486-92. doi: 10.1038/jcbfm.2013.99. Epub 2013 Jun 19. PubMed PMID: 23778163; PubMed Central PMCID: PMC3790940.
Gokina NI, Bonev AD, Gokin AP, Goloman G. Role of impaired endothelial cell Ca(2+) signaling in uteroplacental vascular dysfunction during diabetic rat pregnancy. Am J Physiol Heart Circ Physiol. 2013 Apr 1;304(7):H935-45. doi: 10.1152/ajpheart.00513.2012. Epub 2013 Feb 1. PubMed PMID: 23376827; PubMed Central PMCID: PMC3625897.
Phillips JK, Vance AM, Raj RS, Mandalà M, Linder EA, Gokina NI. Impact of experimental diabetes on the maternal uterine vascular remodeling during rat pregnancy. Reprod Sci. 2012 Mar;19(3):322-31. doi: 10.1177/1933719111424435. PubMed PMID: 22383782; PubMed Central PMCID: PMC3343150.
Mandalà M, Gokina N, Barron C, Osol G. Endothelial-derived hyperpolarization factor (EDHF) contributes to PlGF-induced dilation of mesenteric resistance arteries from pregnant rats. J Vasc Res. 2012;49(1):43-9. doi: 10.1159/000329821. Epub 2011 Oct 6. PubMed PMID: 21985802; PubMed Central PMCID: PMC3221268.

See PubMed listing here.