Bio for Natalia Gokina, Ph.D. Natalia Gokina, Ph.D.Associate ProfessorDepartment of Obstetrics, Gynecology and Reproductive Sciences Contact Information E-mail: Natalia.Gokina@uvm.eduPhone: 802-656-1205Office Location: OB/GYN & Reproductive Sciences, Given Room C-209, 89 Beaumont Avenue, Burlington, VT 05405 Education1985 Ph.D. - Ukranian Academy of Sciences, Kiev, Ukraine, Physiology1974 M.S. - Physiology Kiev State University, Kiev, Ukraine1974 B.S. - Kiev State University, Kiev, Ukraine, PhysiologyResearch InterestsDr. Gokina’s primary research interest is in cardiovascular physiology, specifically, control of vascular smooth muscle and endothelial cell calcium and membrane potential during pregnancy, and in the signal transduction mechanisms underlying arterial reactivity. Current research in Dr. Gokina’s lab is focused on understanding cellular and molecular mechanisms of uteroplacental vascular dysfunction in diabetic pregnancy.Research GrantsNIH, National Heart, Blood, and Lung Institute Calcium Signaling in the Cerebrovascular Unit in Health and Disease (PI: Cipolla)Collaborator: Natalia Gokina, Ph.D. 07/2010 - 06/2015PublicationsGokina NI, Chan SL, Chapman AC, Oppenheimer K, Jetton TL, Cipolla MJ. Inhibition of PPAR? during rat pregnancy causes intrauterine growth restriction and attenuation of uterine vasodilation. Front Physiol. 2013 Jul 23;4:184. doi: 10.3389/fphys.2013.00184. eCollection 2013. PubMed PMID: 23888144; PubMed Central PMCID: PMC3719025.Cipolla MJ, Sweet JG, Gokina NI, White SL, Nelson MT. Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation. J Cereb Blood Flow Metab. 2013 Oct;33(10):1486-92. doi: 10.1038/jcbfm.2013.99. Epub 2013 Jun 19. PubMed PMID: 23778163; PubMed Central PMCID: PMC3790940.Gokina NI, Bonev AD, Gokin AP, Goloman G. Role of impaired endothelial cell Ca(2+) signaling in uteroplacental vascular dysfunction during diabetic rat pregnancy. Am J Physiol Heart Circ Physiol. 2013 Apr 1;304(7):H935-45. doi: 10.1152/ajpheart.00513.2012. Epub 2013 Feb 1. PubMed PMID: 23376827; PubMed Central PMCID: PMC3625897.Phillips JK, Vance AM, Raj RS, Mandalà M, Linder EA, Gokina NI. Impact of experimental diabetes on the maternal uterine vascular remodeling during rat pregnancy. Reprod Sci. 2012 Mar;19(3):322-31. doi: 10.1177/1933719111424435. PubMed PMID: 22383782; PubMed Central PMCID: PMC3343150.Mandalà M, Gokina N, Barron C, Osol G. Endothelial-derived hyperpolarization factor (EDHF) contributes to PlGF-induced dilation of mesenteric resistance arteries from pregnant rats. J Vasc Res. 2012;49(1):43-9. doi: 10.1159/000329821. Epub 2011 Oct 6. PubMed PMID: 21985802; PubMed Central PMCID: PMC3221268.See PubMed listing here.