Bio for Rae Nishi, Ph.D. Rae Nishi, Ph.D.ProfessorDepartment of Neurological SciencesDirector, Neuroscience Graduate Program Contact Information E-mail: Rae.Nishi@uvm.eduOffice Location: Neurological Sciences, HSRF 406, 149 Beaumont Ave., Burlington, Vt WebsiteLab: http://www.uvm.edu/medicine/neuro/?Page=nishilab.htmlEducationPh.D., University of California, San Diego, 1980Postdoctoral training, Harvard Medical SchoolAcademic InterestsI am the director of three advanced graduate courses: Topics in Developmental Neurobiology (NSCI320), Neurochemistry (NSCI 323), and Being a Scientist: Responsible Conduct in Biomedical Research (NSCI 327). I also oversee small group discussions for first year medical students in the Neural Science course of the Vermont integrated Curriculum. I am very interested in promoting outreach in neuroscience to K-12 students and the public. In 2011, I was elected a member of the Dana Alliance for the Brain Initiative, a program of the Dana Foundation.Research InterestsMy research focuses on the role of nicotinic acetylcholine receptors (nAChRs) in neural development and CNS function using a multidisciplinary approach that includes molecular biology, immunohistochemistry, confocal microscopy, cell culture, transgenic mice, and chicken embryos.Administrative InterestsI am the director of the Neuroscience Graduate Program and director of the Neuroscience, Behavior and Health Initiative at UVM.Academic AppointmentsCollege of Medicine Faculty Appointment: July 1, 2001Co-director, Summer Neurobiology Course, MBL, Woods Hole, MA 2004-2007Assistant, Associate, and full Professor, Dept. Cell and Developmental Biology, Oregon Health Sciences University, 1986-2001PublicationsSimpson J, Keefe J and Nishi R. 2013. Differential Effects of Ret and TrkB on Axonal Branching and Survival of Parasympathetic Neurons. Dev. Neurobiol 73:45-59. Epub 2012 Jul 20. PMC in processDeWitt J, Ochoa V, Urschitz J, Elston M, Moisyadi S, and Nishi R. 2013. Constitutively active TrkB confers an aggressive transformed phenotype in a normal neural crest derived cell line. Ocogene. [Epub ahead of print], PMC in processNishi R, Stubbusch J, Hulce JJ, Hruska M, Pappas A, Bravo MC, Huber LP, Bakondi B. Soltys J, Rohrer H. 2010. The cortistatin gene PSS2 rather than the somatostatin gene PSS1 is strongly expressed in developing avian autonomic neurons. J Comp Neurol. 518:839-850. PMC2919489Hruska M, Keefe J, Wert D, Tekinay AB, Hulce JJ, Ibañez-Tallon I, Nishi R. (2009). Prostate stem cell antigen is an endogenous lynx1-like prototoxin that antagonizes alpha7-containing nicotinic receptors and prevents programmed cell death of parasympathetic neurons. J Neurosci., 29(47):14847-54. PMID: 19940180.Hruska M. and Nishi R. (2007). Cell-Autonomous Inhibition of a7-Containing Nicotinic Acetylcholine Receptors Prevents Death of Parasympathetic Neurons during Development. J. Neurosci. 27(43):11501-11509.Straub J., Sholler, G. and Nishi, R. (2007). Embryonic sympathoblasts transiently express TrkB in vivo and proliferate in response to brain-derived neurotrophic factor in vitro. BMC Dev Biol. 7:10-23. To view more of Dr. Nishi's publications, please visit PubMed.