Rheumatology and Clinical Immunology : University of Vermont

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Department of Medicine

Rheumatology and Clinical Immunology

Bio for Ralph Budd, M.D.

Ralph Budd, M.D.

Professor of Medicine and Unit Director, Immunobiology Medicine
Department of Medicine

Contact Information

E-mail: ralph.budd@uvm.edu
Office Location: D-305B Given Bldg., 89 Beaumont Ave., Burlington, VT 05405-0068

Education

1969-1970 M.I.T., Cambridge, MA
1970-1973 B.A. (Biology), Cornell University, Ithaca, NY
1973-1977 M.D., Cornell University Medical College, New York, NY

Research Interests

Dear receptors, caspase regulation, and gd T cell function in infection and autoimmunity

Academic Appointments

1988-1989 Scientist, Division of Molecular Immunology, Genentech, Inc. Clinical Assistant Professor of Medicine, Stanford University School of Medicine, Stanford CA.
1989-1992 Assistant Professor of Medicine, Department of Medicine, The University of Vermont College of Medicine, Burlington, VT.
1992-1997 Associate Professor of Medicine, Department of Medicine, The University of Vermont College of Medicine, Burlington, VT
1995-present Director, Immunobiology Program, Department of Medicine, The University of Vermont College of Medicine, Burlington, VT
1995-present Associate Chair of Research Training, Department of Medicine, The University of Vermont College of Medicine, Burlington, VT
1997-present Professor of Medicine, Department of Medicine, The University of Vermont College of Medicine, Burlington, VT

Awards and Honors

1974-1977 Joseph Collins Foundation Scholar, Cornell Medical College.
1983-1986 Arthritis Foundation Postdoctoral Fellow Member.
1989-1992 RJR Nabisco Research Scholars Award in Immunology.
1990-1994 Pew Scholars Program Award in the Biomedical Sciences.
1998-1999 Fogarty International Fellow, Institute of Biochemistry, University of Lausanne, Lausanne, Switzerland

Publications

Wu W, Misra RS, Russell JQ, Flavell RA, Rincon M, Budd RC. Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3. J. Biol.Chem. 281:10682-10690, 2006.

Budd, R.C., Yeh, W-C, and Tschopp, J. cFLIP regulation of lymphocyte activation and development. Nature Rev. Immunol. 6:196-204, 2006.

Shi, C., Wolfe, J., Russell, J.Q., Hardin, N., Collilns, C., Anguita, J., and Budd, R.C. Fas-Ligand deficiency impairs host inflammatory response against infection with the spirochete, Borrelia burgdorferi. Infect. Immun 74:1156-1160, 2006.

Colllins, C., Wolfe, J., Roessner, K., Shi, C., Sigal, L.H., and Budd, R.C. Lyme arthritis synovial T cells instruct dendritic cells via Fas-ligand. J. Immunol. 175:5656-5665, 2005.

Fortner, K.A., and Budd, R.C. The death receptor, CD95 (Fas/APO-1), mediates the deletion of T lymphocytes undergoing homeostatic proliferation. J. Immunol. 175:4374-4382, 2005.

To view more of Dr. Budd's publications, please visit PubMed.