University of Vermont

College of Medicine

Department of Medicine

Primary Care Internal Medicine

Bio for Charles MacLean, M.D.
Charles MacLean, M.D.

Charles MacLean, M.D.

Professor of Medicine, General Internal Medicine & Geriatrics
Department of Medicine
Associate Dean for Primary Care

Contact Information

Office Location:
Med-General Internal Med, UVMMC-Arnold 5413


1978 Undergraduate: B.Sc., Chemistry. University of New Hampshire
1982 Medical School: MDCM. McGill University, Montreal, Quebec

Academic Interests

Outcomes research
Shared Decision Making
Clinical Decision Support and Office System Design
Blueprint Executive Committee

Academic Appointments

1988-94 Assistant Professor Internal Medicine, University of Vermont/Fletcher Allen Health Care, Burlington VT
1995-2009 Associate Professor Internal Medicine, University of Vermont/Fletcher Allen Health Care, Burlington VT
1988-present Attending Physician, University of Vermont Medical Center, Burlington, VT
1994-present Physician manager, Primary Care Internal Medicine-Essex
2009 - Present Professor of Medicine

Research Grants

1 R01 DK61167-01 (Littenberg) 5/1/02-10/30/05 40% Co-Investigator and Project Director National Institute of Diabetes and Digestive and Kidney Disease (NIH) $2,031,287 total Vermont Diabetes Information System The project will implement and evaluate a state-wide system to support evidence-based disease management by primary care providers, their practices, and their patients in the community. The primary study question is: "What is the effect of a Diabetes Information System (including education, feedback and decision support) upon disease control measured by glycated hemoglobin?" Secondary questions address the effect of the system upon adherence to guideline recommendations, blood pressure control, patient satisfaction, medication use, and functional status. Evaluation will include a prospective randomized trial of the system in 10,000 patients across Vermont.

E11 CC120011-01 (Littenberg) 9/30/01 –9/29/02 20% Co-InvestigatorCenters for Disease Control $266,781 totalAn Information System to Reduce Errors in Diabetes Care Our primary goal is to improve clinical outcomes by developing a detailed understanding of the patterns of error in diabetes care. We propose modifying an existing information system to characterize the current quality of care and incidence of error, and to identify cases with apparent error. We will use root cause analysis techniques to investigate the individual cases and aggregate the patterns of error and failure over the set of cases. Finally, we will use the information and insights developed to propose systematic approaches to error reduction and quality improvement in diabetes care.

Diabetes Case Management in Primary Care. 7/1/01-6/30/02, Donated 10% PI Vermont Health Foundation $40,000 This is a pilot randomized trial of pharmacist case management of patients with diabetes in a primary care setting.

Feasibility of the Vermont Diabetes Registry: a 1-year Pre-Post Intervention Pilot Study of a Concurrent Reminder System and Searchable Data Base in Two Primary Care Practices. 1/1/99-12/30/00Office of Patient Oriented Research – FAHC $15,000 Donated 15% PI

Local co-investigator: A double blind placebo controlled study to assess the safety and further define the clinically effective dose range of MK-0966 in patients with osteoarthritis of the knee or hip. Merck & Co., 1997. (Cox-2 inhibitor)

Local co-investigator: A placebo and active comparator controlled, parallel group six week double blind study to assess the safety and efficacy of MK-0966 vs ibuprofen in patients with OA of the knee or hip. Merck & Co., 1996. (Cox-2 inhibitor)

Awards and Honors

1978 Phi Beta Kappa


Lemaire F; Richalet JP; Carlet J; Brun-Buisson C; MacLean C. Postoperative hypoxemia due to opening of a patent foramen ovale confirmed by a right atrium-left atrium pressure gradient during mechanical ventilation. Anesthesiology 1982;57(3):233-6.

MacLean CD. Principles of cancer screening. Med Clin North America 1996; 80: 1-14.

Demers D, Clark N, Tolzmann G, MacLean C, Benedini K, Farnham P, Plant-Dehays A, Nagy P. Computer simulated cost effectiveness of care management strategies on reduction of long-term sequelae in patients with NIDDM. Qual Management in Health Care 1997; 6: 1-13.

Alkhatib O, Golding L, Maclean C, Moses P. Idiopathic Colonic Varices as a Cause of Lower Gastrointestinal Bleeding in a 36 Year Old Female Patient. Am J. Gastroenterology 1997; 92 (A)

MacLean C D, Susi B, Phifer N, Schultz L, Bynum D, Franco M, Klioze, Monroe M, Garrett J, Cykert S. Religion and Spirituality in the Medical Encounter: Results from a Multicenter Patient Survey. J Gen Int Med. 2003; 18: 38-43.

To view more of Dr. MacLean's publications, please visit PubMed.