University of Vermont

College of Medicine

Department of Medicine


clinical trials

Clinical Trials


Status: Active - Recruiting
Observational Study in Patients with Autosomal Dominant Polycystic Kidney Disease (OVERTURE)
Purpose: To collect characteristics of patients with ADPKD across a broad population, over time to better understand disease progression (signs, symptoms and outcomes). Association with total kidney volume changes and other measures of disease progression will be determined in order to identify a population at increased risk for disease progression. The economic and quality life impact of ADPKD will be assessed. Subjects who terminated participation early from clinical trials with tolvaptan may also be followed. Identifier: NCT01430494
Primary/Site/Co Investigator: Wolfgang J. Weise, M.D.
Contact: Patricia Murray, R.N., 802-847-4095
Information on this trial:
Status: Active - Not Recruiting
A Three-Period, 58-Week Safety and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD) on Dialysis
Purpose: This trial is a three-period, multicenter, safety and efficacy clinical trial. The first period is a two-week Washout Period, the second period is a 52-week randomized, open-label, active control Safety Assessment Period, and the third period is a four-week, randomized, open-label, placebo-controlled Efficacy Assessment Period in only the patients who were randomized to treatment with ferric citrate during the Safety Assessment Period. The primary objectives of this trial are to determine the long-term safety over 52 weeks of up to twelve (12) caplets/day of KRX-0502 (ferric citrate) in patients with ESRD undergoing either hemodialysis or peritoneal dialysis and to determine the efficacy of KRX-0502 (ferric citrate) in the four-week, randomized, open-label, placebo-controlled Efficacy Assessment Period. Identifier: NCT01191255
Primary/Site/Co Investigator: Dana Negoi, M.D.
Contact: Patricia Murray, R.N., 802-847-4095
Information on this trial:

Status: Not Active - Not Recruiting
Blood Pressure Monitoring Program Quality Improvement Project
Purpose: To increase the percent of people with CKD attending renal clinic who have BP at goal by encouraging patient participation in their care Identifier: tbd
Primary/Site/Co Investigator: Virginia Hood, M.D., M.B.B.S
Contact: Suzanne Lapointe, R.N., 802-847-3572
Information on this trial: All patients who attend the Nephrology Clinic can participate

Last modified July 06 2015 03:51 PM