Pathogenetic mechanism of ischemic injury to the kidney.
Long-term survival of kidney transplants and recipients of kidney transplant.
Tubular and vascular pathogenesis of ischemic acute kidney injury and repair.
Mechanism of reduction in renal solute clearance in acute kidney injury and chronic kidney disease.Biomarkers of kidney injury.
Dr. Kwon has been interested in elucidating pathophysiologic mechanism of ischemic injury to the kidney, especially in kidney transplants. She has published noble data of tubular and vascular injury and repair, and associated derangement in physiology of the freshly transplanted kidneys. She also published data on urinary biomarkers monitoring the current status of acute kidney injury and delayed kidney graft function due to ischemic injury. She has been a reviewer for journals in Nephrology. She has been a transplant nephrologist for the recent 15 years, evaluating patients with advanced stage of chronic kidney disease for kidney transplantation and taking care of recipients of kidney and/or pancreas transplant.
University of Vermont, Associate Professor of Medicine
Fletcher Allen Health Care, Department of Medicine, Division of Nephrology and Hypertension1. Ramesh G, Kwon O, Ahn K. Netrin-1: A Novel Universal Biomarker of Human Kidney Injury. Transplantion Proceedings 42: 1519-1522, 2010.
2. Kwon O, Ahn K, Zhang B, Lockwood T, Dhamija R, Anderson D, Saqib N. Simultaneous Monitoring of Multiple Urinary Cytokines may Predict Renal and Patient Outcome in Ischemic AKI. Renal Failure 32(6): 699-708, 2010.
3. Kwon O, Miller S, Li N, Khan A, Kadry Z, Uemura T. Bone marrow-derived endothelial progenitor cells and endothelial cells may contribute to endothelial repair in the kidney immediately after ischemic-reperfursion. J Histochem Cytochem 58: 687-694, 2010. First publiched on March 30, 2010.
4. Uemura T, Liang J, Khan A, Kwon O, Ghahramani N, Wang L, Hollenbeak C, Reeves B, Kadry Z. Outcomes of transplantation of single pediatric renal allografts equal to or more than 6 cm in length. Transplantion 89 (6): 710-713, 2010.
5. Kwon O, Hong S-M, Ramesh G. Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia/reperfusion. Am J Physiol 296: F25-F33, 2009. First published on October 29, 2008.