University of Vermont

College of Medicine

Department of Medicine

Endocrinology, Diabetes & Metabolism

Bio for C. Lawrence Kien, M.D., Ph.D.
C. Lawrence Kien, M.D., Ph.D.

C. Lawrence Kien, M.D., Ph.D.

Department of Pediatrics
Department of Medicine
Division of Endocrinology

Contact Information
Office Location:
UVM Colchester Research Facility, 208 South Park Drive, Rm 175A, Colchester, VT 05446


Ph.D., Nutritional Biochemistry and Metabolism, MIT, Cambridge, MA (1977)
M.D., University of Cincinnati College of Medicine, Cincinnati, OH (1972)
B.S. in Zoology, Duke University, Durham, NC (1968)

Academic Interests

Research: Effects of long and short chain fatty acids on metabolism and on risks of obesity and type 2 diabetes.
Teaching: Clinical nutrition deficiences, obesity, type 2 diabetes, roles of the colon in human nutrition.

Academic Appointments

Professor, Departments of Pediatrics and Medicine, University of Vermont College of Medicine, Burlington, VT (2004-present)
The Mary Kay Davignon Green and Gold Professor, University of Vermont College of Medicine (2005-present)

Research Grants

Palmitate metabolism and insulin resistance (Kien, PI)

Mechanisms for differential effects of dietary fatty acids on metabolism (Kien, PI)

Awards and Honors

Clinical and Integrative Diabetes and Obesity (CIDO) Study Section (Regular Member) (07/01/2007 - 06/30/2011)
National Board of Medical Examiners (NBME)
Biochemistry Test Committee, National Board of Medical Examiners (NBME) (1998-2002)
Step 1 Test Material Development Committee for Biochemistry United States Medical Licensing Examination (USMLE) (1998-2002)

Consultant (for Carbohydrates) Term Panel, Life Sciences Research Office (FASEB), (Advisory to FDA) (1996 - 2001)
Ad Hoc Expert Panel: Review of infant formula nutrient requirements for preterm infants, Life Sciences Research Office (FASEB), (Advisory to FDA)
Ad Hoc Review of the USMLE Step 1 Pass/Fall Standard (April, 2000)
Nutrition Study Section (1989 - 1993)
Special Fellow, Leukemia Society of America, Inc. (1981)
Future Leaders Award, The Nutrition Foundation, Inc. (1980)

Publications (Peer Reviewed)

Kien CL, Everingham KI, D Stevens R, Fukagawa NK, Muoio DM, Short-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects. Obesity. 2011; 19:305-311.

Kien CL, Bunn JY. Gender alters the effects of palmitate and oleate on fat oxidation and energy expenditure. Obesity. 2008; 16:29-33.

Schmidt DE, Allred JB, Kien CL. Fractional oxidation on chylomicron-derived oleate is higher than palmitate in healthy adults fed small, frequent meals. J Lipid Res. 1999; 40:2322-2332.

Kien CL, Ault K, McClead RE. In vivo estimation of lactose hydrolysis in premature infants using a dual stable tracer technique. Am J Physiol Endocrinol Metab. 1992; 263:E1002-E1009.

Kien CL. Isotopic dilution of CO2 as an estimate of CO2 production during substrate oxidation studies. Am J Physiol. 1989; 257:E296-E298.

For a complete list of Dr. Kien's publications, please visit Pub Med