University of Vermont

College of Medicine

Department of Medicine

Endocrinology, Diabetes & Metabolism

Bio for Tom Jetton, Ph.D.
Tom Jetton, Ph.D.

Tom Jetton, Ph.D.

Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism

Contact Information
Office Location:
UVM Colchester Research Facility, 360 South Park Drive, Colchester, VT 05446


B.S. in Biology, University of North Carolina at Charlotte, Charlotte, NC, 1980

M.S. in Biology, Western Carolina University, Cullowhee, NC; Thesis Advisor, Dr F.W. Harrison, 1983

Ph.D. in Biology, Vanderbilt University, Nashville, TN; Dissertation Advisor, Dr B.J. Bogitsh, 1990

Postdoctoral Fellow in Molecular Physiology/Biophysics, Vanderbilt University, Nashville, TN; Mentor, Dr M.A. Magnuson, 1990-1993

Academic Interests

Developmental and regeneration biology of the pancreatic islets
Glucose homeostasis
Beta cell mass compensation


Molecular, cellular, and physiological approaches to study the regulation of pancreatic beta cell growth and survival.

Academic Appointments

Professor, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, 2015-present
Associate Professor,  Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, 1999-2015

Research Grants

ß-cell Compensation in Partial Pancreatectomy Mice (Leahy, PI)
Jetton, Co-I

Beta-cell PPAR gamma signaling in fat fed mice (Leahy, PI)
Jetton, Co-I
ADA Basic Research Grant

PPARy and uterine vascular dysfunction in diabetic pregnancy (Gokina, PI)
Jetton, Co-I

Additive effects of TZD and DPP-4 inhibitor therapy on beta-cell mass and function (Leahy, PI)
Jetton, Co-I
Takeda Pharmaceuticals Research Grant

Awards and Honors

Phi Kappa Phi Honor Society, 1984

Publications (Peer Reviewed)

Jetton TL, Liu YQ, Trotman WE, Nevin PW, Sun X-J, Leahy JL. Enhanced insulin receptor substrate-2 expression and activation of protein kinase B/Akt in the regenerating pancreatic duct epithelium of 60% partial pancreatectomy rats. Diabetologia. 2001; 44:2056-2065.

Jetton TL, Lausier J, LaRock K, Trotman WE, Larmie B, Habibovic A, Peshavaria M, Leahy JL. Mechanisms of compensatory ß-cell growth in insulin resistant rats: Roles of Akt kinase. Diabetes. 2005; 54:2294-2304.

Peshavaria M, Larmie BL, Lausier J, Satish B, Habibovic A, Roskens V, LaRock K, Everill B, Leahy JL, Jetton TL. Regulation of pancreatic ß-cell regeneration in the normoglycemic 60% partial pancreatectomy mouse. Diabetes. 2006; 55:3289-3298.

Jetton TL, Everill B, Lausier J, Roskens V, Habibovic A, LaRock K, Gokin A, Peshavaria M, Leahy JL. Enhanced ß-cell mass without increased proliferation following chronic mild glucose infusion. Am J Physiol Endocrinol Metab. 2008; 294:E679-687.

Lausier J, Diaz WC, Roskens V, LaRock K, Herzer K, Fong CG, Latour M, Peshavaria M, Jetton TL. Vagal control of pancreatic ß-cell proliferation. Am J Physiol Endocrinol Metab. 2010; 299:E786-E793.

For a complete list of Dr. Jetton's publications, please visit Pub Med