University of Vermont

College of Medicine

Department of Medicine

Cardiovascular Medicine

Bio for Peter C Van Buren
Peter C Van Buren

Peter C Van Buren

Associate Professor of Medicine
Cardiovascular Medicine, Department of Medicine
Assistant Professor of Molecular Physiology & Biophysics

Contact Information
Office Location:
Medicine, MFU-McClure Wing


University of Vermont, Burlington, VT

Research Interests

Delineated the role of sarcomeric proteins in the contractile deficit of human myocardial failure. With the use of human myocardial biopsy samples and an in vitro model of muscle contraction, Dr. VanBuren has identified key molecular defects in the contractile machinery. This knowledge can be applied to emerging therapies that specifically target maladapted myocardial signaling pathways. Through such an approach improved survival in patients with heart failure may ultimately be achieved.

Academic Appointments

Associate Professor of Medicine
Associate Professor of Molecular Physiology and Biophysics


VanBuren P, Palmer BM. Cooperative Activation of the Cardiac Myofilament: The Pivotal Role of Tropomyosin. Circulation. 2010;121:351-3.

Donaldson C, Taatjes DJ, Zile M, Palmer B, VanBuren P, Spinale F, Maughan D, Von Turkovich M, Bishop N, LeWinter MM. A Combined Immunoelectron Microscopic and Stereologic Method to Detect Advanced Glycation End-Products in Human Myocardium. Histochem Cell Biol. 2010;134:23-30

Hünlich M, Tremble SM, Begin KJ, Leavitt BJ, Ittleman FP, VanBuren P. Atrial Contractile Protein Content and Function are Preserved in Patient with Coronary Artery Disease and Atrial Fibrillation. Coron Artery Dis. 2010;21:357-62.

Miller MS, VanBuren P, LeWinter MM, Braddock JM, Ades PA , Maughan DW, Palmer BM, Toth MJ. Chronic heart failure decreases cross-bridge kinetics in single skeletal muscle fibers from humans. J Physiol. 2010 In press

VanBuren P, LeWinter MM. Heart Failure as a Consequence of Diabetic Cardiomyopathy. In Heart Failure: A Companion to Braunwald’s Heart Disease. Mann D, editor. 2010 In press.

For a complete listing of publications go to