University of Vermont

College of Medicine

Department of Medicine

Cardiovascular Medicine

Bio for William Hopkins, M.D.
William Hopkins, M.D.

William Hopkins, M.D.

Associate Professor of Medicine
Cardiovascular Medicine, Department of Medicine

Contact Information
Office Location:
Medicine-Cardiology, McClure Wing, 111 Colchester Avenue, Burlington, VT 05401


University of Chicago, Chicago, IL

Research Interests

Dr. Hopkins is committed to advancing knowledge in the fields of congenital heart disease, pulmonary hypertension, and Down syndrome.  He has a research interest in Eisenmenger Syndrome, cyanotic congenital heart disease, pulmonary hypertension, and Down syndrome.

Academic Appointments

Associate Professor of Medicine
Director, Pulmonary Hypertension and Adult Congenital Heart Disease Program


Hopkins WE, Ochoa LL, Richardson GW, Trulock EP.  Severe pulmonary artery hypertension:  A comparison of hemodynamics and survival of adults with primary pulmonary hypertension or Eisenmenger Syndrome.  J Heart Lung Transplant 1996;15:100-105.

Hopkins WE, Hall C.  Paradoxical relationship between N-terminal proatrial natriuretic peptide and filling pressure in adults with cyanotic congenital heart disease.  Circulation 1997;96:2215-20.

Hopkins WE, Sobel BE, Schneider DJ.  Plasminogen activator inhibitor type 1 in adults with Down Syndrome and protection against macrovascular disease.  Am J Cardiol 2000;85:784-6.

Hopkins WE, Waggoner AD.  Severe pulmonary hypertension without right ventricular failure: The unique hearts of patients with the Eisenmenger Syndrome. Am J Cardiol 2002;89:34-8.

Hopkins WE, Chen Z, Fukagawa N, Hall C, Knot H, LeWinter M.  Increased atrial and brain natriuretic peptides in adults with cyanotic congenital heart disease: Enhanced understanding of the relationship between hypoxia and natriuretic peptide secretion. Circulation 2004;109:2872-7.

Hopkins WE. The remarkable right ventricle of patients with Eisenmenger Syndrome.  Coron Artery Dis 2005;16:19-25.

Rubin LJ, Hopkins WE. In: UpToDate, Rose BD (ed), UpToDate, Waltham, MA 2007-present.
     - Overview of Pulmonary Hypertension
     - Diagnostic Evaluation of Pulmonary Hypertension
     - Pathogenesis of Pulmonary Hypertension
     - Treatment of Pulmonary Hypertension

Hopkins WE. Medical Students, Intellectual Curiosity, and Algorithmic Medicine: Reflections of a Teacher. Coron Artery Dis 2009;20:477-8.

Hopkins WE.  Right ventricular performance in congenital heart disease: A physiologic and pathophysiologic perspective.  Cardiol Clin 2012;30:205-18. 

Preston IR, Klinger JR, Hopkins WE, Hill NS.  Obesity and pulmonary hypertension.  European Resp Monogr 2012;57:194-207. 

Altman R, Strand V, Hochberg M, Gibofsky A, Markenson J, Hopkins WE, Cryer B, Kivitz A, Nezzer J, Imasogie O, Young C.  Low-dose Solumatrix diclofenac in the treatment of osteoarthritis: a 1-year, open-label, phase III safety study.  Postgrad Med 2015;127:517-28. 

Jennings D, Seibyl J, Sabbagh M, Lai F, Hopkins WE, Bullich S, Gimenez M, Reininger C, Putz B, Stephens A, Catafau A, Marek K.  Age-dependent of brain beta-amyloid deposition in Down syndrome: a [18F]florbetaben PET study.  Neurology 2015;84:500-7.