University of Vermont

College of Medicine

Tracy Coauthors Nature Study on Rare Genetic Mutations Associated with Heart Attack

New research findings indicate that LDL – the “bad” cholesterol – may have company as a major risk factor for heart attacks that occur at an early age. The new culprit: a mutation in VLDL – or very low-density lipoprotein – a group of triglyceride-rich lipoproteins. The study is published in the February 5, 2015 issue of Nature. Read the full story.

Laboratory for Clinical Biochemistry Research

Advancing Biomedical Science

The Laboratory for Clinical Biochemistry Research (LCBR) focuses on understanding risk factors for heart disease, stroke, venous thrombosis, obesity, diabetes, aging, and frailty using a wide variety of assays in population and family-based research settings, particularly in the areas of coagulation, fibrinolysis, thrombosis, inflammation, and immune system function. These results are linked to animal model studies, especially research in murine atherosclerosis

Study Data

Clinical Studies

The Laboratory research portfolio includes molecular and genetic epidemiology family-based genetic research, clinical trials and basic studies using murine models of disease.


Technical Information

The LCBR Faculty and staff has accumulated a vast amount and diverse range of experience working with and developing multitudes of clinical assays, including information regarding Luminex Validation, and Luminex Validation Data by Analyte.

Mary Cushman, M.D., M.Sc., with student


The Laboratory staff have collaborated on a wide variety of clinical studies, clinical trials, and epidemiology studies on local, national, and international scales.

Last modified December 12 2013 02:35 PM