Freeman Laboratory - Department of Surgery
Grants, Collaborations, Abstracts, Publications & Honors
Grants
Surgical Research Award - Freeman (PI)
Department of Surgery 07/01/2009 – 06/30/2011 $17,744
Cardiac magnetic resonance imaging to determine left ventricular function in a rodent model of traumatic brain injury
Investigator-Initiated Research Grant - Freeman (PI)
Masimo Corporation 04/01/10 – 4/02/10 $99,873
Evaluation of Masimo noninvasive carboxyhemoglobin testing in ED patients with suspected
carbon monoxide poisoning
Clinical Scientist Research Career Development Award (K08) - Freeman (PI)
NIH/NIGMS 07/01/2011-06/30/2016 $629,600
Endothelial Ca2+ signals and vasodilatory function after traumatic brain injury
Center of Biomedical Research Excellence (COBRE) in Neuroscience Pilot Project - Freeman (PI)
College of Medicine 07/01/2011-06/30/2012 $63,387
Endothelial Ca2+ signals and blood brain barrier permeability following traumatic brain injury
Surgical Research Award – Freeman (PI)
Department of Surgery 07/01/2011 – 06/30/2013 $25,000
A randomized-controlled trial of cognitive therapy to enhance neural repair and improve clinical outcomes following traumatic brain injury
Collaborations
Dept. of the Army - Mann/ Brummel-Zeidins (Co-PIs) (Biochemistry)
Dept. of Defense 3/1/10-2/28/13
Systems Biology for Biological Responses to Severe Hemorrhage $1,864,341
RO1 Naylor (PI) (Psychiatry)
NIH/ NIAMS 7/1/10-6/30/15 $3,263,379
Can therapy alter CNS processing of chronic pain: A longitudinal study
Recent Abstracts
Larson BE, Hannah RM, Sonkusare SK, Wellman GC, Nelson MT, Freeman K. Endothelial Ca2+ signals and vasodilatory function following traumatic brain injury. FASEB J (2011; 25; 641.24 abstract)
Loadholt CD, Larson BE, Andriakos PG, Boas S, Trahan TE, Tran TL, Falls WA, Hammack SE, Freeman K. Inter-rater reliability of a novel neurobehavioral scale for outcomes assessment in rats following traumatic brain injury. FASEB J (2011; 25; 856.5 abstract)
Larson B, Beal A, Ahari A, Russell S, Freeman K. Beta-adrenergic blockade prevents myocardial oxidative stress due to traumatic brain injury. Annals of Emergency Medicine (2008; 54(3): S142-143 abstract)
Moore HB, Dorf L, Streeter MH, Destigter KK, Crookes B, Leffler S, Freeman K. Airway, breathing, CT scanning: duplicate computed tomography imaging after transfer to trauma center. Journal of Surgical Research (2011;165(2), 341 abstract)
Publications
Larson BE, Stockwell DW, Boas S, Andrews T, Wellman GC, Lockette W, Freeman K. Cardiac reactive oxygen species after traumatic brain injury. J of Surgical Research (2011, Epub ahead of print). PMID: 22172132
Blum JA, Freeman K, Dart RC, Cooper RJ. Requirements and Definitions in Conflict of Interest Policies of Medical Journals. JAMA, Nov 25, 2009; 302(20):1-5. PMID: 19934424
Freeman K, Feldman JA, Mitchell P, Donovan J, Dyer KS, Eliseo L, White L, and Temin E. Effects of clinical presentation and initial electrocardiogram on time-to-treatment in emergency department patients with hyperkalemia, Academic Emergency Medicine (2008, 5(3):239-49). PMID: 18304054
Freeman K, Feldman JA. Cocaine, myocardial infarction, and beta blockade: Time to rethink the equation? Annals of Emergency Medicine (2008, 51:130-134.). PMID: 17933425
Freeman K, Dewitz A, Baker W. Ultrasound-guided hip arthrocentesis in the emergency department. The American Journal of Emergency Medicine (2007, 25: 80-86). PMID: 17157689
Sandhu H, Carpenter C, Freeman K, Nabors SG, Olson A. Clinical decisionmaking: opening the black box of cognitive reasoning. Annals of Emergency Medicine. 2006 Dec;48(6):713-9. PMID: 17112935
Freeman K, Lerman I, Kranias EG, Bohlmeyer T, Bristow MR, Lefkowitz RJ, Iaccarino G, Koch WJ, and Leinwand LA. Alterations in cardiac adrenergic signaling and calcium cycling have markedly different effects on the progression of hypertrophic cardiomyopathy, The Journal of Clinical Investigation (2001, 107: 967-974). PMID: 11306600
Freeman K, Colon-Rivera C, Olsson MC, Moore RL, Weinberger HD, Grupp IL, Vikstrom K, Iaccarino G, Koch WJ, and Leinwand LA. Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene, The American Journal of Physiology (2001, 280: H151-H159). PMID: 11123229
Freeman K, Nakao K, Leinwand LA. Low sequence variation in the human cardiac b-myosin heavy chain gene, Genomics (2001, 76: 73-80). PMID: 11549319
Lerman I, Harrison B, Freeman K, Hewett TE, Allen DL, Robbins J, Leinwand LA. Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains, The Journal of Applied Physiology (2002, 92: 2245-2255). PMID: 12015333
Freeman K, Farrow S, Schmaier A, Freedman R, Schork T, and Lockette W. Genetic polymorphism of the a2 -adrenergic receptor is associated with increased platelet aggregation, baroreceptor sensitivity, and salt excretion in normotensive humans, The American Journal of Hypertension (1995, 8:863-869). PMID: 8541000
Honors
James E. Demeules Surgical Research Award, University of Vermont (2009, 2010)
Tram L Tran (undergraduate) - Woodworth Prize and Honors College Award for physiology research in laboratory (2011)
Ali Sadeghi (undergraduate)- Honors College Award for MRI research (2011)
Last modified March 20 2012 06:12 PM


