Recent research:
High speed video imaging of calcium signaling events in the vascular endothelium following traumatic brain injury.
Freeman Laboratory - Department of Surgery
Kalev Freeman is Principal Investigator of the Trauma Physiology Laboratory and Director of Emergency Medicine Research
Our overall goal is to perform novel research that will improve outcomes for patients with brain trauma or other acute injuries.
Ongoing studies are focused on:
1. Effects of traumatic brain injury (TBI) on endothelial Ca2+ signals and vasodilatory function
2. Cerebrovascular endothelium and barrier function in TBI
3. Cognitive therapy and MRI for TBI
Effects of TBI on blood vessels
Goal: To elucidate the mechanistic basis and functional consequence of changes in vascular physiology following acute brain injury.
Cerebrovascular endothelium
Goal: To understand the changes in cerebrovascular endothelial Ca+2 signals, vasodilation, and blood brain barrier permeability after acute brain injury.
Cognitive therapy and MRI
Goal: To test the hypothesis that recovery from brain trauma involves neural repair and plasticity, detectable by neuroimaging and enhanced by cognitive therapy.
Last modified September 07 2012 02:09 PM
