University of Vermont

College of Medicine

Freeman Laboratory

Freeman Laboratory - Department of Surgery

Kalev Freeman is Principal Investigator of the Trauma Physiology Laboratory in the Department of Surgery.

The laboratory focuses on studying the fundamental vascular biology changes that occur following trauma. Our overall goal is to improve outcomes for patients with traumatic injuries.

Effects of trauma on blood vessels

Goal: To elucidate the mechanistic basis and functional consequence of changes in vascular physiology following acute brain injury.

Cerebrovascular pathology

Goal: To understand the changes in cerebrovascular endothelial Ca+2 signals, vasodilation, and blood brain barrier permeability after acute brain injury.

Artery

Role of endothelium in trauma induced coagulopathy

Goal: To determine the effects of histones, polyphosphates, and thrombin on native endothelium in trauma.

Last modified January 03 2014 11:25 AM