A Mission to Foster Cardiovascular Research
The Cardiovascular Research Institute of Vermont (CVRI-VT) exists to foster cardiovascular research at The University of Vermont. As an organization, it is broadly inclusive of investigators at the University of Vermont who are pursuing cardiovascular research and includes and serves members of multiple departments.
Our key objectives are to:
- improve communication, particularly across disciplines, departments, and colleges;
- increase collaboration;
- increase funding to support cardiovascular research; and
- advance and highlight excellence in research nationally and internationally.
*NOTE* Trainees and junior investigators presenting at scientific meetings are encouraged to apply for travel awards.
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» CVRI joins the UVM College of Medicine and the UVM Medical Center as a co-sponsor of the American Heart Association's "Go Red for Women" luncheon.
Dr. Schneider's lab is working to elucidate factors that modulate platelet function, to associate platelet function with cardiovascular events, and to evaluate the impact of therapeutic agents on platelet function.
Above, Dr. Schneider has added a sample of whole blood to a tube containing platelet-identifying antibodies and activation-specific antiplatelet markers, and he is now gently flicking the bottom of the tube to mix the contents. The tube will then rest for 15 minutes at room temperature before the contents are fixed, diluted, and analyzed in the flow cytometer to assess the level of platelet activation.
Research in the Nelson lab is focused in 3 main areas: understanding the control of smooth muscle and endothelial cell function by ion channel and calcium signaling; understanding “vascular crosstalk”—how sympathetic nerves, smooth muscle, and endothelial cells communicate to control the function of resistance-sized peripheral arteries; and understanding the basic mechanisms for ion channel control of vascular function to gain insight into pathologies and possible new therapeutic interventions.
Click here to learn more about the work being done in Dr. Nelson’s lab.
The Warshaw lab studies how myosin-binding protein C (MyBP-C) (red/ yellow structure) modulates the heart’s contraction. With mutations to the MyBP-C gene linked to sudden death in young athletes, the Warshaw Lab is working to unravel how MyBP-C interacts with myosin, the heart’s tiny molecular motor, to tune cardiac performance on a beat-to-beat basis.
Last modified January 30 2015 11:31 AM