University of Vermont

College of Medicine

Department of Biochemistry

This page has moved to here!


Key Publications

Mason, A.B., Byrne, S.L., Everse, S.J., Roberts, S.E., Chasteen, N.D., Smith, V.C., MacGillivray, R.T., Kandemir, B., and Bou-Abdallah, F., A loop in the N-lobe of human serum transferrin is critical for binding to the transferrin receptor as revealed by mutagenesis, isothermal titration calorimetry, and epitope mapping. J Mol Recognit. 2009 Nov-Dec;22(6):521-9

Byrne, S.L., Chasteen, N.D., Steere, A.N., and Mason, A.B., The unique kinetics of iron release from transferrin: the role of receptor, lobe-lobe interactions, and salt at endosomal pH. J Mol Biol. 2010 Feb 12;396(1):130-40

James, N.G., Ross, J.A., Mason, A.B., and Jameson, D.M., Excited-state lifetime studies of the three tryptophan residues in the N-lobe of human serum transferrin. Protein Sci. 2010 Jan;19(1):99-110

Steere, A.N., Roberts, S.E., Byrne, S.L., Dennis, C.N., Bobst, C.E., Kaltashov, I.A., Smith, V.C., MacGillivray, R.T., and Mason, A.B., Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin. Protein Expr Purif. 2010 Jul;72(1):32-41

Leverence, R., Mason, A.B., Kaltashov, I.A., Noncanonical interactions between serum transferrin and transferrin receptor evaluated with electrospray ionization mass spectrometry. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8123-8

Yoon, D.J., Kwan, B.H., Chao, F.C., Nicolaides, T.P., Phillips, J.J., Lam, G.Y., Mason, A.B., Weiss, W.A., and Kamei, D.T., Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery. Cancer Res. 2010 Jun 1;70(11):4520-7

Byrne, S.L., Steere, A.N., Chasteen, N.D., and Mason, A.B., Identification of a kinetically significant anion binding (KISAB) site in the N-lobe of human serum transferrin. Biochemistry. 2010 May 18;49(19):4200-7

Eckenroth BE, Mason AB, McDevitt ME, Lambert LA, Everse SJ.The structure and evolution of the murine inhibitor of carbonic anhydrase: a member of the transferrin superfamily. Protein Sci. 2010 Sep;19(9):1616-26. doi: 10.1002/pro.439.PMID: 20572014

Rooijakkers SH, Rasmussen SL, McGillivray SM, Bartnikas TB, Mason AB, Friedlander AM, Nizet V.Human transferrin confers serum resistance against Bacillus anthracis. J Biol Chem. 2010 Sep 3;285(36):27609-13. Epub 2010 Jul 8. PMCID: PMC2934628

Steere AN, Byrne SL, Chasteen ND, Smith VC, MacGillivray RT, Mason AB. Evidence that His349 acts as a pH-inducible switch to accelerate receptor-mediated iron release from the C-lobe of human transferrin. J Biol Inorg Chem. 2010 Nov;15(8):1341-52. Epub 2010 Aug 14. PMID: 20711621

Eckenroth BE, Steere AN, Chasteen ND, Everse SJ, Mason AB. How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13089-94. Epub 2011 Jul 25. PMCID: PMC3156180

Steere AN, Miller BF, Roberts SE, Byrne SL, Chasteen ND, Smith VC, MacGillivray RT, Mason AB. Ionic residues of human serum transferrin affect binding to the transferrin receptor and iron release. Biochemistry. 2012 Jan 17;51(2):686-94. Epub 2012 Jan 6. PMCID: PMC3267578

Sheftel AD, Mason AB, Ponka P. The long history of iron in the Universe and in health and disease. Biochim Biophys Acta. 2012 Mar;1820(3):161-87. Epub 2011 Aug 9. PMCID: PMC3258305

Steere AN, Byrne SL, Chasteen ND, Mason AB. Kinetics of iron release from transferrin bound to the transferrin receptor at endosomal pH. Biochim Biophys Acta. 2012 Mar;1820(3):326-33. Epub 2011 Jun 15. PMCID: PMC3253137

Noinaj N, Easley NC, Oke M, Mizuno N, Gumbart J, Boura E, Steere AN, Zak O, Aisen P, Tajkhorshid E, Evans RW, Gorringe AR, Mason AB, Steven AC, Buchanan SK. Nature. 2012 Feb 12;483(7387):53-8. doi: 10.1038/nature10823. PMCID: PMC3292680

All Publications

Last modified May 26 2016 03:49 PM