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  1. Li D, Pan Y, Duan Y, Hung Z, Xu M, He L. Understanding SARS with Wolfram approach. Acta Biochimica et Biophysica Sinica. 2004 Jan;36(1):1-10. PMID: 14732867.
  2. Liu X, He G, Wang X, Chen Q, Qian X, Lin W, Li D, Gu N, Feng G, He L. Association of DAAO with schizophrenia in the Chinese population. Neuroscience Letters. 2004 Oct 21;369(3):228-33. PMID: 15464270.
  3. Yang Y, Xiao Z, Chen W, Sang H, Guan Y, Peng Y, Zhang D, Gu Z, Qian M, He G, Qin W, Li D, Gu N, He L. Tumor suppressor gene TP53 is genetically associated with schizophrenia in the Chinese population. Neuroscience Letters. 2004 Oct 14;369(2):126-31. PMID: 15450681.


  1. Pan Y, Li D, Duan Y, Zhang Z, Xu M, Feng G, He L. Predicting protein subcellular location using digital signal processing. Acta Biochimica et Biophysica Sinica. 2005 Feb;37(2):88-96. PMID: 15685365.
  2. Liu X, Qin W, He G, Yang Y, Chen Q, Zhou J, Li D, Gu N, Xu Y, Feng G, Sang H, Hao X, Zhang K, Wang S, He L. A family-based association study of the MOG gene with schizophrenia in the Chinese population. Schizophrenia Research. 2005 Mar 1;73(2-3):275-80. PMID: 15653272.
  3. Liu J, Shi Y, Tang W, Guo T,Li D, Yang Y, Yang Y, Zhao X, Wang H, Li X, Feng G, Gu N, Zhu S, Liu H, Guo Y, Shi J, Sang H, Yan L, He L. Positive association of the human GABA-A-receptor beta 2 subunit gene haplotype with schizophrenia in the Chinese Han population. Biochemical and Biophysical Research Communications. 2005 Sep 2;334(3):817-23. PMID: 16023997.


  1. Li D, Sham PC, Owen MJ, He L. Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human Molecular Genetics. 2006 Jul 15;15(14):2276-84. PMID: 16774975. (cited 531 times in Google Scholar)
  2. Li D, Collier DA, He L. Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia. Human Molecular Genetics. 2006 Jun 15;15(12):1995-2002. PMID: 16687441. (cited 313 times in Google Scholar)
  3. Li D, He L. Further clarification of the contribution of the tryptophan hydroxylase (TPH) gene to suicidal behavior using systematic allelic and genotypic meta-analyses. Human Genetics. 2006 Apr;119(3):233-40. PMID: 16450114.
  4. Liu X, Li H, Qin W, He G, Li D, Shen Y, Shen J, Gu N, Feng G, He L. Association of TPH1 with suicidal behaviour and psychiatric disorders in the Chinese population. Journal of Medical Genetics. 2006 Feb;43(2):e4. PMID: 16467214. PMCID: PMC2564644.
  5. Li D, He L. Meta-analysis shows association between the tryptophan hydroxylase (TPH) gene and schizophrenia. Human Genetics. 2006 Aug;120(1):22-30. PMID: 16741719.
  6. Li D, He L. Association study of the G-protein signaling 4 (RGS4) and proline dehydrogenase (PRODH) genes with schizophrenia: a meta-analysis. European Journal of Human Genetics. 2006 Oct;14(10):1130-5. (Nature Publishing Group) PMID: 16791139.
  7. Li D, Duan Y, He L. Association study of serotonin 2A receptor (5-HT2A) gene with schizophrenia and suicidal behavior using systematic meta-analysis. Biochemical and Biophysical Research Communications. 2006 Feb 17;340(3):1006-15. PMID: 16405867.
  8. Zhang X, Li D, Duan S, Duan Y, Chen Q, Li X, Liu Z, Feng G, He L. Analysis of the association between Apolipoprotein D and schizophrenia. Neuropsychobiology. 2006Nov;54(1):40-4. PMID: 16966838.


  1. Li D, He L. Meta-analysis supports association between serotonin transporter (5-HTT) and suicidal behavior. Molecular Psychiatry. 2007 Jan;12(1):47-54. PMID: 16969368. (cited 172 times in Google Scholar)
  2. Li D*, He L. G72/G30 genes and schizophrenia: a systematic meta-analysis of association studies. Genetics. 2007 Feb;175(2):917-22. PMID: 17179078. PMCID: PMC1800627. (* corresponding author)
  3. Li D*, He L*. Association study between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia: a meta-analysis. Schizophrenia Research. 2007 Nov;96(1-3):112-8. PMID: 17604607. (*co-corresponding author)
  4. Li D*, He L*. Association study between the NMDA receptor 2B subunit gene (GRIN2B) and schizophrenia: a HuGE review and meta-analysis. Genetics in Medicine. 2007 Jan;9(1):4-8. PMID: 17224684. (*co-corresponding author)


  1. Levran O, O'Hara K, Peles E, Li D, Barral S, Ray B, Borg L, Ott J, Adelson M, Kreek MJ. ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence. Human Molecular Genetics. 2008 Jul 15;17(14):2219-27. PMID: 18424454. PMCID: PMC2599947.
  2. Li D*, He L*. Meta-study on association between the monoamine oxidase A gene (MAOA) and schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2008 Mar 5;147B(2):174-8. PMID: 17894408. (* co-corresponding author)


  1. Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nature Genetics. 2009 Jun;41(6):703-7. PMID: 19430480. PMCID: PMC2889014. Note: name was shown in the author list of the consortium as supplementary information.
  2. Li D*, Feng G, He L*. Case-control study of association between the functional candidate gene ERBB3 and schizophrenia in Caucasian population. World Journal of Biological Psychiatry. 2009;10(4 Pt 2):595-8. PMID: 19995212. (* co-corresponding author)
  3. Li D*, He G, Xu Y, Duan Y, Gu N, Li X, Shi Y, Qin W, Feng G, He L. Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies. Genetics and Molecular Biology. 2009 Oct;32(4):729-30. PMID: 21637446. PMCID: PMC3036886. (* co-corresponding author)
  4. He C, Hamon S, Li D, Barral S, Ott J. MHC fine mapping of human type 1 diabetes using the T1DGC data. Diabetes, Obesity and Metabolism. Vol 11, Suppl 1, 2009 Jan, 53-9. PMID: 19143815. PMCID: PMC2753855.


  1. Bertisch H, Li D, Hoptman MJ, Delisi LE. Heritability estimates for cognitive factors and brain white matter integrity as markers of schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2010 Jun 5;153B(4):885-94. PMID: 20052692. PMCID: PMC3446203.
  2. Proudnikov D, Kroslak T, Sipe JC, Randesi M, Li D, Hamon S, Ho A, Ott J, Kreek MJ. Association of polymorphisms of the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes with heroin addiction: impact of long repeats of CNR1. Pharmacogenomics Journal. 2010 Jun;10(3):232-42. PMID: 20010914.
  3. Hilner JE, Perdue LH, Sides EG, Pierce JJ, Wägner AM, Aldrich A, Loth A, Albret L, Wagenknecht LE, Nierras C, Akolkar B; Type 1 Diabetes Genetics Consortium. Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC). Clinical Trials. 2010;7(1 Suppl):S5-S32. PMID: 20603248. Note: name was shown in the author list of the consortium as supplementary information.


  1. Li D*, Zhao H, Gelernter J. Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. Biological Psychiatry. 2011 Sep 15;70(6):504-12. PMID: 21497796. PMCID: PMC3142297. (* corresponding author)
  2. Cui D, Zhang H, Yang BZ, Listman JB, Li D, Price LH, Carpenter LL, Tyrka AR, Anton RF, Kranzler HR, Gelernter J. Variation in NGFB is associated with primary affective disorders in women. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2011 Jun;156B(4):401-12. PMID: 21294249. PMCID: PMC3108453.


  1. Li D, Zhao H, Kranzler HR, Oslin D, Anton RF, Farrer LA, Gelernter J. Association of COL25A1 with comorbid antisocial personality disorder and substance dependence. Biological Psychiatry. 2012 Apr 15;71(8):733-40. PMID: 22297151. PMCID: PMC3548659.
  2. Li D*, Zhao H, Gelernter J. Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases. Human Genetics. 2012 Aug;131(8):1361-74. PMID: 22476623. PMCID: PMC3557796. (* corresponding author)
  3. Li D*, Zhao H, Gelernter J. Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians. Human Genetics. 2012 May;131(5):725-37. PMID: 22102315. PMCID: PMC3548401. (* corresponding author)
  4. Zhang H, Li D, Su Y, Jiang S, Xu Y, Jiang K, Cui D. Identification of the N-acylsphingosine amidohydrolase 1 gene (ASAH1) for susceptibility to schizophrenia in a Han Chinese population. World Journal Biological Psychiatry. 2012 Feb;13(2):106-13. PMID: 21375364.


  1. Cao J, Hudziak J, Li D*. Multi-cultural Association of the Serotonin Transporter Gene (SLC6A4) with Substance Use Disorder. Neuropsychopharmacology. 2013 Aug;38(9):1737-47. PMID: 23518607. PMCID: PMC3717550. (* corresponding author)
  2. Cao J, LaRocque E, Li D*. Associations of the 5-hydroxytryptamine (Serotonin) Receptor 1B Gene (HTR1B) with Alcohol, Cocaine, and Heroin Abuse. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2013 Mar;162(2):169-76. PMID: 23335468. PMCID: PMC4089973. (* corresponding author)
  3. Wang L, Jiao Y, Huang Y, Liu X, Gibson G, Bennett B, Hamre KM, Li D, Zhao H, Gelernter J, Kranzler HR, Farrer LA, Lu L, Wang Y, Gu W. Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations. Genetics and Molecular Research. 2013 Nov 26;12(4):5992-6005. PMID: 24338393.


  1. Sulovari A, Li D*. GACT: a Genome build and Allele definition Conversion Tool for SNP imputation and meta-analysis in genetic association studies. BMC Genomics. 2014 Jul 19;15(1):610. PMID: 25038819. (* corresponding author)
  2. Yang H, Li D, Cheng C. Relating gene expression evolution with CpG content changes. BMC Genomics. 2014 Aug 20;15(1):693. PMID: 25142157. PMCID: PMC4148958.
  3. Li D*, Sulovari A, Cheng C, Zhao H, Kranzler HR, Gelernter J. Association of Gamma-Aminobutyric Acid A Receptor α 2 Gene (GABRA2) with Alcohol Use Disorder. Neuropsychopharmacology. 2014 Mar;39(4):907-18. PMID: 24136292. PMCID: PMC3924525. (* corresponding author)
  4. Cao J, Liu X, Han S, Zhang CK, Liu Z, Li D*. Association of the HTR2A gene with alcohol and heroin abuse. Human Genetics. 2014 Mar;133(3):357-65. PMID: 24178752. PMCID: PMC4085799. (* corresponding author)


  1. Li D*, Zhao H, Kranzler HR, Li M, Jensen KP, Zayats T, Farrer LA, Gelernter J. Genome-wide Association Study of Copy Number Variations (CNVs) With Opioid Dependence. Neuropsychopharmacology. 2015 Mar;40(4):1016-26. PMID: 25345593. PMCID: PMC4330517. (* corresponding author)
  2. Sulovari A, Kranzler HR, Farrer LA, Gelernter J, Li D*. Eye Color: A Potential Indicator of Alcohol Dependence Risk in European Americans. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2015 2015 Jul;168(5):347-53. (* corresponding author). Recommended on F1000Prime as among top articles in Medicine (http://f1000.com/prime/725513049?key=Gtg2Fsi8Ry6WWi9). Ranked #1 of 465, the highest scoring article in this journal that Altmetric has tracked so far (http://www.altmetric.com/details.php?domain=onlinelibrary.wiley.com&citation_id=3953354). On ScienceDaily June 30, 2015 (http://www.sciencedaily.com/releases/2015/06/150630135258.htm). Yahoo Health (https://www.yahoo.com/health/this-eye-color-is-linked-to-alcoholism-122943625863.html). Featured on July 1 in the science section of The Huffington Post (www.huffingtonpost.com/2015/07/01/blue-eyes-alcoholic-light-colored-eyes_n_7705806.html). Burlington free press (http://www.burlingtonfreepress.com/story/news/local/2015/07/02/uvm-viral-eye-color-alcohol/29646245). ABC news (http://abcnews.go.com/Health/link-eye-color-alcoholism-risk-revealed-study/story?id=32190705). WCAX news (http://www.wcax.com/story/29472056/sunday-science-link-between-eye-color-and-alcoholism). CBS News (http://www.cbsnews.com/news/what-eye-color-may-reveal-about-the-risk-of-alcoholism). Tampa Bay Times (http://www.tampabay.com/news/health/genetic-study-leads-to-an-intriguing-question-do-blue-eyes-make-you-a/2236096). WPTZ-TV (http://www.wptz.com/news/study-blue-eyes-linked-to-higher-rates-of-alcoholism/33952058).


  1. Sulovari A, Chen YH, Hudziak JJ, Li D*. Atlas of human diseases influenced by genetic variants with extreme allele frequency differences. Human Genetics. 2017 Jan;136(1):39-54. PMID: 27699474. (* corresponding author).
  2. Sulovari A, Liu Z, Zhu Z*, Li D*. Genome-wide meta-analysis of copy number variations with alcohol dependence. Pharmacogenomics Journal. 2017 Jul 11. [Epub ahead of print] PMID: 28696413. (* corresponding author).


   45 Cao J, Li D*. Searching for human oncoviruses: histories, challenges, and opportunities. (* corresponding author). Journal of Cellular Biochemistry. (A review paper). In Press.