University of Vermont

University of Vermont Clinical Research Center

Areas of Research

CRC Research

 

Study Highlights:    Current research being conducted on the CRC.

Bibliography:         Some publications resulting from research on the CRC

Areas of Interest:

Cardiac Disease: Cardiac function in heart failure; cardiac rehabilitation.

Clinical Pharmacology: Phase I and II drug trials.

Gastroenterology: Regional enteritis; immune studies of chronic active hepatitis; effect of diet on colonic mucosa.

Gynecology: Estrogen metabolism in postmenopausal women; prostaglandin synthetase inhibitors; modulating role of body composition on reproductive hormones; effect of estrogen on cardiac function.

Metabolism: Obesity; hypoglycemia; diabetes mellitus; exercise; genetic studies in multiple endocrine neoplasia; catecholamine metabolism; regulation of energy expenditure; ketoacid effects on amino acid metabolism in insulin-dependent diabetes mellitus; protein metabolism-regulation of protein synthesis and degradation by hormones and substrates; interactions between diabetes and thromboses.

Neurology: Therapeutic intervention in idiopathic chronic polyneuropathy; DNA damage in muscular dystrophy, polymyositis, amyotrophic lateral sclerosis, Alzheimer's and Parkinson's diseases.

Nutrition: Pathophysiology of weight gain; obesity; diet-induced thermogenesis; dietary fiber; nutrition support; effect of dietary fiber on estrogen metabolism; effects of vitamin K1 in women of childbearing age; low-calorie versus low-fat diets; effects of tryptophan depletion on behavior.

Oncology: Clinical trials of chemotherapeutic agents and immunotherapy; intraperitoneal IL-2 and lymphokine-activated killer cells in recurrent ovarian carcinoma; lymphatic scintigraphy.

Pediatrics: Hormonal mechanisms of pubertal growth; relation of age-related decline in growth hormone to muscle loss and fat accumulation; treatment of obesity with growth hormone; testing for prediabetes.

Psychiatry: Bulimia and anorexia nervosa: treatment comparison; stimulant and alcohol interactions; mecamylamine model of dementia; effect of nicotine administration on cognitive functions in Alzheimer's disease; genetic basis of aggression in children; substance abuse; drug discrimination.

Surgery: Subcutaneous heparin versus oral warfarin in patients undergoing unilateral elective knee or hip replacement surgery.

Last modified December 19 2014 11:31 AM

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