Dr. Lounsbury received her B.S. in Biochemistry at Penn State in 1987 and her Ph.D. in Pharmacology at the University of Pennsylvania in 1993. She trained as a postdoc at the University of Vermont with Dr. Ian Macara from 1993-1997 and with Drs. Mark Nelson and Joseph Brayden from 1997-1998. She received her appointment to Assistant Professor of Pharmacology at UVM in 1998 and was promoted to Associate Professor with tenure in 2004.

Research Interests

The overall goal of our research program is to define specific signal transduction patterns that relate to changes in gene expression in vascular smooth muscle. The intent of the research is to better understand signals generated under normal physiological versus pathological conditions to identify potential targets for both cancer and cardiovascular therapies. The research can be roughly divided into 3 project areas: 1) Calcium Regulated Gene Transcription in Vascular Smooth Muscle; 2) Signaling in Lung Epithelial Injury Proliferation and Fibrosis; 3) Regulation of Tumor Angiogenesis: Vascular Cell Responses to Hypoxia. The future directions of these projects include defining mechanisms of signaling pathways using molecular and cellular biology as well as exploring pharmacologic targets using animal models and clinical correlations.

Integrating Cell Biology, Biochemistry and Molecular Biology