A unique aspect of the CMB Program is the interdisciplinary nature of the individual research projects, which are often highly collaborative and cross traditional department boundaries. A number of participating faculty have primary appointments in clinical as well as basic science departments, bringing a broad perspective of contemporary problems in cell, molecular and biomedical sciences.

The research enterprise in the CMB Program is well-funded by extramural support in the form of individual research awards, program projects grants, and pre- and post-doctoral training grants. Funding sources include the National Institutes of Health, National Science Foundation, American Heart Association, USDA and NASA. Large interdisciplinary, multi-investigator grants fund research projects in cancer biology, cardiovascular biology and cell motility, environmental pathology, immunobiology, neuroscience, and pulmonary function and disease.

In addition, students have access to cutting-edge equipment and focused training in our core facilities. These facilities include the Bioinformatics, X-Ray Crystallography, DNA Analysis, Flow Cytometry, Microscopy and Imaging, and Transgenic Mice cores.

Note: Faculty listed below have self identified their participation in these areas, and may be listed in multiple categories. For an alphabetical list of faculty, please visit the faculty directory.

 

Faculty Research Listed by Topic Area

Cancer Biology and Genome Stability Plant and Cell Biology
Immunology and Microbial Pathogenesis Proteomics and Bioinformatics
Lung and Cardiovascular Biology Structural Biology and Biophysics


UVM CMB Cancer Biology & Genomics
Bryan Ballif Molecular Mechanisms of Signal Transduction
Ralph Budd Death receptor regulation of apoptosis in the immune system
Frances Carr Cellular events which mediate thyroid hormone action in development and pathophysiology
Sylvie Doubli� X-Ray Crystallography
Barry Finette Mutagenic Mechanisms in Pediatric Diseases
Christopher Francklyn Structure and Function of Nucleic Acid Binding Proteins
Karen Glass Structure and function of epigenetic reader domains
Nicholas Heintz Cell cycle control
Robert Hondal Mechanism of Thioredoxin Reductase — a Collaborative Project
Alan Howe Regulation of cell migration by extracellular matrix
David Krag Development of Targeted Therapeutics
Christopher Landry Materials Chemistry, Nanotechnology, and Particles in Biology
Jane Lian
Matthew Lord Role of myosin motors in the cell.
Karen Lounsbury Vascular Smooth Muscle Signaling: Tumor Angiogenesis and Atherosclerosis
Scott Morrical DNA Repair- structure and function of protein-DNA complexes
David Pederson DNA Replication and Repair in Chromatin
Mercedes Rincon Signaling and gene regulation in thymus development, activation, differentiation and death of CD4+ and CD8+ T cells
Arti Shukla Understanding Pathogenesis of mesothelioma and identifying appropriate thearapeutic strategies
Girja Shukla Cancer-specific affinity molecules for diagnosis and targeted therapy
Gary Stein Cancer, Stem Cell and Bone Biology Program
Janet Stein Regulation of Gene Expression during the Cell Cycle and during the Proliferation/Differentiation Transition
Jason Stumpff Molecular Control of Cell Division
Susan Wallace DNA Damage and Repair
UVM CMB Immunology & Microbial Pathogenesis
John Barlow Mathematical and molecular epidemiology of infectious disease; Host-Pathogen interactions in mastitis; Cattle MHC
Elizabeth Bonney Maternal immunity and tolerance
Jason Botten Host immune response to viral infection, the basis of persistent viral infection in reservoir hosts, host-pathogen interactions, and the development of novel therapeutic agents and vaccines
Jonathan Boyson Molecular and Genetic Determinants of iNKT Cell Function
Ralph Budd Death receptor regulation of apoptosis in the immune system
John Burke Ribozymes and RNA Structure
Terrence Delaney Pathogen-induced disease resistance in plants
Sean Diehl Vaccines and immunology
Mary Dunlop Synthetic Biology; Feedback Loops in Gene Regulation
Sally Huber Coxsackievirus induced autoimmune heart disease and atherosclerosis
Christopher Huston Host-Pathogen Interactions of Intestinal Protozoa
Charlie (Charles) Irvin Asthma Pathogenesis, respiratory physiology and airway biology.
Douglas Johnson Yeast Biofilm Formation and Virulence
David Kerr Innate Immunity to Dairy Mastitis
Keith Mintz Molecular Mechanisms of Bacterial Pathogenesis
Matthew Poynter Airway epithelium in innate and adaptive immune responses
Mercedes Rincon Signaling and gene regulation in thymus development, activation, differentiation and death of CD4+ and CD8+ T cells
Teresa Ruiz Structural and Functional Studies of Macromolecular Complexes
Aimee Shen Sporulation and spore germination in the nosocomial pathogen Clostridium difficile
Girja Shukla Cancer-specific affinity molecules for diagnosis and targeted therapy
Benjamin Suratt Host factors and their effects on innate immunity and lung inflammation and injury
Cory Teuscher Genetics of susceptibility to infectious and autoimmune disease
Markus Thali Research Interests
Gary Ward Cell Biology of Host-Parasite Interaction
Matthew Wargo Regulation of Bacterial Virulence and Catabolism
Daniel Weiss Gene and stem cell therapies for lung diseases.
André-Denis Wright Gastrointestinal Microbiology
UVM CMB Lung & Cardiovascular Biology
Vikas Anathy Endoplasmic Reticulum (ER) Based Chaperones and Protein Disulfide Isomerases in Lung Diseases
Beth Bouchard Mechanisms regulating factor V endocytosis by megakaryocytes
Joe Brayden Pharmacology: Ionic mechanisms of vasoconstriction and vasodilation in cerebral arterioles
Frances Carr Cellular events which mediate thyroid hormone action in development and pathophysiology
Marilyn Cipolla
Wolfgang Dostmann cGMP/PKG signaling in vascular smooth muscle; Pharmacology
Stephen Everse Structure & Function of Proteins
Kalev Freeman Trauma physiology/ traumatic brain injury
Nicholas Heintz Cell cycle control
Sally Huber Coxsackievirus induced autoimmune heart disease and atherosclerosis
Charlie (Charles) Irvin Asthma Pathogenesis, respiratory physiology and airway biology.
Yvonne Janssen-Heininger Transcriptional regulators of lung responses to injury and inflammation
Robert Kelm Regulation of Cell Differentiation by ssDNA/RNA-Binding Proteins
Karen Lounsbury Vascular Smooth Muscle Signaling: Tumor Angiogenesis and Atherosclerosis
Mark Nelson Pharmacology – Understanding the control of smooth muscle and endothelial cell function by ion channels and calcium signaling.
Matthew Poynter Airway epithelium in innate and adaptive immune responses
Michael Radermacher Structure determination and functional studies of macromolecular assemblies using 3DEM
Mercedes Rincon Signaling and gene regulation in thymus development, activation, differentiation and death of CD4+ and CD8+ T cells
Teresa Ruiz Structural and Functional Studies of Macromolecular Complexes
Arti Shukla Understanding Pathogenesis of mesothelioma and identifying appropriate thearapeutic strategies
Jay Silveira Biochemistry of Platelet Function
Benjamin Suratt Host factors and their effects on innate immunity and lung inflammation and injury
Doug Taatjes Cell imaging and disease
Cory Teuscher Genetics of susceptibility to infectious and autoimmune disease
Michael Toth Translational studies of human skeletal muscle structure and function
Paula Tracy Biochemistry of Platelet Function
Russell Tracy
Kathleen Trybus Molecular motors and their tracks
Albert van der Vliet Biological and environmental oxidants and airway inflammation: Mechanisms of redox signaling
Jim Vigoreaux Biology of insect flight muscle and vertebrate cardiac muscle
Matthew Wargo Regulation of Bacterial Virulence and Catabolism
David Warshaw Myosin Molecular Motors
Daniel Weiss Gene and stem cell therapies for lung diseases.
George Wellman Cerebral artery function in health and disease
UVM CMB Plant & Cell Biology
Vikas Anathy Endoplasmic Reticulum (ER) Based Chaperones and Protein Disulfide Isomerases in Lung Diseases
Jason Botten Host immune response to viral infection, the basis of persistent viral infection in reservoir hosts, host-pathogen interactions, and the development of novel therapeutic agents and vaccines
Ralph Budd Death receptor regulation of apoptosis in the immune system
Terrence Delaney Pathogen-induced disease resistance in plants
Wolfgang Dostmann cGMP/PKG signaling in vascular smooth muscle; Pharmacology
Barry Finette Mutagenic Mechanisms in Pediatric Diseases
Jeanne Harris Developmental Genetics of Legume Root Nodules
Nicholas Heintz Cell cycle control
Alan Howe Regulation of cell migration by extracellular matrix
Yvonne Janssen-Heininger Transcriptional regulators of lung responses to injury and inflammation
Thomas Jetton Mechanisms that regulate the development, growth, and regeneration of pancreatic beta cells
Jane Lian
Steven Lidofsky Mechanisms of cell volume regulation in liver
Matthew Lord Role of myosin motors in the cell.
Karen Lounsbury Vascular Smooth Muscle Signaling: Tumor Angiogenesis and Atherosclerosis
Anthony Morielli Pharmacology
Jill Preston
Mercedes Rincon Signaling and gene regulation in thymus development, activation, differentiation and death of CD4+ and CD8+ T cells
Aimee Shen Sporulation and spore germination in the nosocomial pathogen Clostridium difficile
Arti Shukla Understanding Pathogenesis of mesothelioma and identifying appropriate thearapeutic strategies
Gary Stein Cancer, Stem Cell and Bone Biology Program
Janet Stein Regulation of Gene Expression during the Cell Cycle and during the Proliferation/Differentiation Transition
Jason Stumpff Molecular Control of Cell Division
Doug Taatjes Cell imaging and disease
Markus Thali Research Interests
Mary Tierney Mechanisms for controlling cell function through ECM structure
Michael Toth Translational studies of human skeletal muscle structure and function
Albert van der Vliet Biological and environmental oxidants and airway inflammation: Mechanisms of redox signaling
Judy Van Houten

Susan Wallace DNA Damage and Repair
Gary Ward Cell Biology of Host-Parasite Interaction
David Warshaw Myosin Molecular Motors
UVM CMB Proteomics & Bioinformatics
Bryan Ballif Molecular Mechanisms of Signal Transduction
Jeffrey Bond Structural Biology of Proteins and DNA
Jason Botten Host immune response to viral infection, the basis of persistent viral infection in reservoir hosts, host-pathogen interactions, and the development of novel therapeutic agents and vaccines
John Burke Ribozymes and RNA Structure
Christopher Francklyn Structure and Function of Nucleic Acid Binding Proteins
Dawei Li Human Genetics and Genomics
Dwight Matthews Analytical and clinical applications of mass spectrometry
Neil Sarkar Computational Techniques for Studying Contemporary Biomedical and Biodiversity
Judy Van Houten

UVM CMB Structural Biology & Biophysics
Christopher Berger Molecular Mechanisms of Axonal Transport
John Burke Ribozymes and RNA Structure
Wolfgang Dostmann cGMP/PKG signaling in vascular smooth muscle; Pharmacology
Sylvie Doubli� X-Ray Crystallography
Stephen Everse Structure & Function of Proteins
Christopher Francklyn Structure and Function of Nucleic Acid Binding Proteins
Karen Glass Structure and function of epigenetic reader domains
Robert Hondal Mechanism of Thioredoxin Reductase — a Collaborative Project
Matthew Lord Role of myosin motors in the cell.
Scott Morrical DNA Repair- structure and function of protein-DNA complexes
David Pederson DNA Replication and Repair in Chromatin
Michael Radermacher Structure determination and functional studies of macromolecular assemblies using 3DEM
Teresa Ruiz Structural and Functional Studies of Macromolecular Complexes
Aimee Shen Sporulation and spore germination in the nosocomial pathogen Clostridium difficile
Gary Stein Cancer, Stem Cell and Bone Biology Program
Jason Stumpff Molecular Control of Cell Division
Kathleen Trybus Molecular motors and their tracks
Susan Wallace DNA Damage and Repair
David Warshaw Myosin Molecular Motors

Prospective Students
The CMB Graduate Program is looking to train students who have a passion to learn and want to become successful in the sciences. See if you have the qualifications it takes to earn your PhD with some world-renowned faculty. Read more...
Current Students
The Cellular, Molecular and Biomedical Sciences Graduate Program focuses on several major areas that will contribute to your individual development while earning your PhD and becoming a scientist. Academics, Research and Professional Skills. Read more...