Faculty Investigator: Eyal Amiel, PhD, Assistant Professor, Medical Laboratory and Radiation Science
Dr. Eyal Amiel received his BA in Biology from Amherst College (2002), and received his Ph.D. in Microbiology and Immunology from the Geisel School of Medicine at Dartmouth College (2009). He performed his postdoctoral training at the Trudeau Institute in Saranac Lake, NY prior to joining the faculty of UVM in 2013.Members:
~Phyu Thwe (CMB graduate student)
~Daniel Fritz (Laboratory Research Technician)
~Nick Galasso (Undergraduate Student)
~Alexandra Ojemann (Undergraduate Student)
~Ben Adamik (Undergraduate Student)
Accepting rotation students: No
Major Research Projects:
The primary focus of our laboratory research is to identify novel mechanisms of molecular control of cellular metabolism in dendritic cells and monocytes of the immune system, and to determine how these influence the activation and immune-generating potential of these cells. Our studies, which include analyses of both mouse and primary human immune cells, are focused on the following areas of investigation:
- What are the nutrient requirements that support dendritic cell and monocyte activation and immune function at the cellular level?
- How do changes in cellular metabolism in response to inflammatory signals govern immune activation and cell survival in these cells?
- How can cellular metabolism be manipulated to influence the outcome of immune cell activation (i.e. can metabolic manipulation be used to enhance or dampen immune responses to affect specific target outcomes)?
- CMB graduate student Phyu Thwe joined the lab to perform her dissertation research in May 2014.
- CMB graduate student Phyu Thwe received a scholarship to attend the 55th Annual Short Course on Medical and Experimental Mammalian Genetics hosted by The Jackson Laboratory.
- Dr. Amiel was a co-author an article published in the journal Nature Immunology in February 2014.