Chem143 Syllabus




Date

Topic


August

1

M 30

Carbon Compounds and Chemical Bonds

Chemical bonds, Lewis structures, octet rule (1.1-1.6; 1.10)


September

2

W 1

Carbon Compounds and Chemical Bonds

Formal charge, resonance (1.7-1.9)

3

F 3

Carbon Compounds and Chemical Bonds

Orbitals, hybridization, molecular geometries

M 6

Labor Day - No Class

4

W 8

Representative Carbon Compounds

Carbon-carbon bonds, bond polarities (1.9-1.15)

5

F 10

Representative Carbon Compounds

Functional groups (2.1-2.13; 4.2-4.3)

6

M 13

Representative Carbon Compounds

Functional groups, physical properties (2.14-2.16)

7

W 15

Alkanes

Nomenclature of alkanes and cycloalkanes (4.1-4.4)

8

F 17

Alkanes

Nomenclature of alkenes and alkynes
Physical properties and conformations of alkanes (4.5-4.13)

9

M 20

Alkanes

Conformation (4.5-4.13)

10

W 22

Alkanes

Conformation, synthesis

F 24

Exam 1

11

M 27

Stereochemistry: Chiral Molecules

Isomerism, enantiomers, planes of symmetry (5.1-5.6)

12

W 29

Stereochemistry: Chiral Molecules

R-S nomenclature, optical activty (5.7-5.10)


October

13

F 1

Stereochemistry: Chiral Molecules

Diastereoisomers, Fischer projections, stereoisomerism of cyclic compounds (5.10-5.14)

14

M 4

Organic Reactions: Acids and Bases

Mechanisms, arrows, acid-base reactions (3.1-3.5)

15

W 6

Organic Reactions: Acids and Bases

Ka, pKa, structure and stability (3.5-3.10)

F 8

Fall Recess - No Class

16

M 11

Organic Reactions: Acids and Bases

Carboxylic acids, non-aqueous solutions

17

W 13

Ionic Reactions: Reactions of Alkyl Halides

Alkyl halides, nucleophiles and leaving groups
SN2 reaction kinetics and mechanism (6.1-6.8)

18

F 15

Ionic Reactions: Reactions of Alkyl Halides

SN1 reaction mechanism, carbocations (6.8-6.14)

19

M 18

Ionic Reactions: Reactions of Alkyl Halides

Factors affecting rates of SN1 and SN2 reactions (6.12-6.14)

20

W 20

Ionic Reactions: Reactions of Alkyl Halides

E1 and E2 reactions, substitution vs. elimination (6.15-6.19)

F 22

Exam 2

21

M 25

Alkenes and Alkynes: Properties and Synthesis

E-Z nomenclature, relative stabilities, dehydrohalogenation, E2 mechanism (7.1-7.6)

22

W 27

Alkenes and Alkynes: Properties and Synthesis

Dehydration of alcohols, carbocation rearrangements (7.7-7.8)

23

F 29

Alkenes and Alkynes: Properties and Synthesis

Elimination of vicinal dibromides, alkynes (7.9-7.11)


November

24

M 1

Alkenes and Alkynes: Properties and Synthesis

Hydrogenation, index of hydrogen deficiency (7.12-7.15)

25

W 3

Alkenes and Alkynes: Addition Reactions

Addition of HX, Markovnikov's rule (8.1-11)

26

F 5

Alkenes and Alkynes: Addition Reactions

Addition of X2, stereochemistry of addition, halohydrins, carbene and carbenoid formation (8.12-8.15)

27

M 8

Alkenes and Alkynes: Addition Reactions

Oxidations, additions to alkynes (8.16-8.20)

28

W 10

Synthetic Strategies

Retrosynthetis analysis, multistep synthesis (8.21)

F 12

Exam 3

29

M 15

Radical Reactions

Homolysis, radical stability, chlorination (10.1-10.5)

30

W 17

Radical Reactions

Selectivity, radical addition to alkenes (10.6-10.9)

31

F 19

Alcohols and  Ethers

Structure, nomenclature, properties, synthesis (11.1-11.4)

32

M 22

Alcohols and  Ethers

Synthesis, acidity of alcohols, sulfonates (11.5-11.10)

W 24

Thanksgiving - No Class

F 26

Thanksgiving - No Class

33

M 30

Alcohols and  Ethers

Reactions of alcohols, synthesis of ethers, protecting groups (11.11-11.12)


December

34

W 1

Alcohols and  Ethers

Reactions of ethers, epoxides, crown ethers (11.13-11.17)

35

F 3

Alcohols from Carbonyl Compounds

Carbonyl group, oxidation-reduction reactions (12.1-12.4)

36

M 6

Alcohols from Carbonyl Compounds

Alcohols from Grignard reagents (12.5-12.10)